ENZYME entry: EC 2.7.1.153
| Accepted Name | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| phosphatidylinositol-4,5-bisphosphate 3-kinase | |||||||||||||||||||
| Alternative Name(s) | |||||||||||||||||||
| type I phosphoinositide 3-kinase | |||||||||||||||||||
| Reaction catalysed | |||||||||||||||||||
| a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP <=> a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+) | |||||||||||||||||||
| Comment(s) | |||||||||||||||||||
| This enzyme also catalyzes the phosphorylation of PtdIns4P to PtdIns(3,4)P2, and of PtdIns to PtdIns3P. | |||||||||||||||||||
| Cross-references | |||||||||||||||||||
| BRENDA | 2.7.1.153 | ||||||||||||||||||
| EC2PDB | 2.7.1.153 | ||||||||||||||||||
| ExplorEnz | 2.7.1.153 | ||||||||||||||||||
| PRIAM enzyme-specific profiles | 2.7.1.153 | ||||||||||||||||||
| KEGG Ligand Database for Enzyme Nomenclature | 2.7.1.153 | ||||||||||||||||||
| IUBMB Enzyme Nomenclature | 2.7.1.153 | ||||||||||||||||||
| IntEnz | 2.7.1.153 | ||||||||||||||||||
| MEDLINE | Find literature relating to 2.7.1.153 | ||||||||||||||||||
| MetaCyc | 2.7.1.153 | ||||||||||||||||||
| Rhea expert-curated reactions | 2.7.1.153 | ||||||||||||||||||
| UniProtKB/Swiss-Prot |
| ||||||||||||||||||
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