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ENZYME

ENZYME entry: EC 2.7.1.154

Accepted Name
phosphatidylinositol-4-phosphate 3-kinase
Alternative Name(s)
C2-domain-containing phosphoinositide 3-kinase
phosphoinositide 3-kinase
type II phosphoinositide 3-kinase
Reaction catalysed
a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP <=> a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+)
Comment(s)
This enzyme also phosphorylates PtdIns to PtdIns3P.
Cross-references
BRENDA2.7.1.154
EC2PDB2.7.1.154
ExplorEnz2.7.1.154
PRIAM enzyme-specific profiles2.7.1.154
KEGG Ligand Database for Enzyme Nomenclature2.7.1.154
IUBMB Enzyme Nomenclature2.7.1.154
IntEnz2.7.1.154
MEDLINEFind literature relating to 2.7.1.154
MetaCyc2.7.1.154
Rhea expert-curated reactions2.7.1.154
UniProtKB/Swiss-Prot
O00443, P3C2A_HUMANQ61194, P3C2A_MOUSEQ5RAY1, P3C2A_PONAB
O00750, P3C2B_HUMANO75747, P3C2G_HUMANO70167, P3C2G_MOUSE
O70173, P3C2G_RATP48736, PK3CG_HUMANQ9JHG7, PK3CG_MOUSE
O02697, PK3CG_PIG

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.7.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.7.-.-
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