ENZYME entry: EC 2.7.1.154
| Accepted Name |
|---|
| phosphatidylinositol-4-phosphate 3-kinase.
|
| Alternative Name(s) |
|---|
| C2-domain-containing phosphoinositide 3-kinase. |
| phosphoinositide 3-kinase. |
| type II phosphoinositide 3-kinase. |
| Reaction catalysed |
|---|
| a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP <=> a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+) |
| Comment(s) |
|---|
| This enzyme also phosphorylates PtdIns to PtdIns3P.
|
| Cross-references |
|---|
| BRENDA | 2.7.1.154 |
| EC2PDB | 2.7.1.154 |
| ExplorEnz | 2.7.1.154 |
| PRIAM enzyme-specific profiles | 2.7.1.154 |
| KEGG Ligand Database for Enzyme Nomenclature | 2.7.1.154 |
| IUBMB Enzyme Nomenclature | 2.7.1.154 |
| IntEnz | 2.7.1.154 |
| MEDLINE | Find literature relating to 2.7.1.154 |
| MetaCyc | 2.7.1.154 |
| Rhea expert-curated reactions | 2.7.1.154 |
| UniProtKB/Swiss-Prot |
| O00443, P3C2A_HUMAN; | Q61194, P3C2A_MOUSE; | Q5RAY1, P3C2A_PONAB; |
| O00750, P3C2B_HUMAN; | O75747, P3C2G_HUMAN; | O70167, P3C2G_MOUSE; |
| O70173, P3C2G_RAT; | P48736, PK3CG_HUMAN; | Q9JHG7, PK3CG_MOUSE; |
| O02697, PK3CG_PIG; |
|
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