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ENZYME

ENZYME entry: EC 2.7.1.158

PURL: https://purl.expasy.org/enzyme/EC/2.7.1.158
Accepted Name
inositol-pentakisphosphate 2-kinase
Alternative Name(s)
inositol 1,3,4,5,6-pentakisphosphate 2-kinase
inositol polyphosphate kinase
Ins(1,3,4,5,6)P5 2-kinase
IP5 2-kinase
Reaction catalysed
1D-myo-inositol 1,3,4,5,6-pentakisphosphate + ATP = 1D-myo-inositol hexakisphosphate + ADP + H(+)
Comment(s)
  • The enzyme can also use Ins(1,4,5,6)P4 and Ins(1,4,5)P3 as substrate.
  • Inositol hexakisphosphate (phytate) accumulates in storage protein bodies during seed development and, when hydrolyzed, releases stored nutrients to the developing seedling before the plant is capable of absorbing nutrients from its environment.
Cross-references
BRENDA2.7.1.158
EC2PDB2.7.1.158
ExplorEnz2.7.1.158
KEGG Ligand Database for Enzyme Nomenclature2.7.1.158
IUBMB Enzyme Nomenclature2.7.1.158
MEDLINEFind literature relating to 2.7.1.158
MetaCyc2.7.1.158
Rhea expert-curated reactions2.7.1.158
UniProtKB/Swiss-Prot
Q59KN8, IPK1_CANALQ6FRN1, IPK1_CANGAQ6BHL8, IPK1_DEBHA
Q75EW5, IPK1_EREGSQ6CNG8, IPK1_KLULAB8AVX5, IPK1_ORYSI
Q7XQZ6, IPK1_ORYSJQ9USK0, IPK1_SCHPOQ6C6Q7, IPK1_YARLI
Q06667, IPK1_YEASTQ93YN9, IPPK_ARATHP0CO35, IPPK_CRYNB
P0CO34, IPPK_CRYNJQ4JL91, IPPK_DANREQ9W2Q7, IPPK_DROME
Q9H8X2, IPPK_HUMANQ6P1C1, IPPK_MOUSEQ4P4C1, IPPK_MYCMD
Q5PXE9, IPPK_RAT

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.7.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.7.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-