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ENZYME entry: EC 2.7.1.169
Accepted Name |
pantoate kinase.
|
Reaction catalysed |
(R)-pantoate + ATP <=> (R)-4-phosphopantoate + ADP + H(+) |
Comment(s) |
- The conversion of (R)-pantoate to (R)-4'-phosphopantothenate is part
of the pathway leading to biosynthesis of 4'-phosphopantetheine,
an essential cofactor of coenzyme A and acyl-carrier protein.
- In bacteria and eukaryotes this conversion is performed by
condensation with beta-alanine, followed by phosphorylation
(EC 6.3.2.1 and EC 2.7.1.33, respectively).
- In archaea the order of these two steps is reversed,
and phosphorylation precedes condensation with beta-alanine.
|
Cross-references |
BRENDA | 2.7.1.169 |
EC2PDB | 2.7.1.169 |
ExplorEnz | 2.7.1.169 |
PRIAM enzyme-specific profiles | 2.7.1.169 |
KEGG Ligand Database for Enzyme Nomenclature | 2.7.1.169 |
IUBMB Enzyme Nomenclature | 2.7.1.169 |
IntEnz | 2.7.1.169 |
MEDLINE | Find literature relating to 2.7.1.169 |
MetaCyc | 2.7.1.169 |
Rhea expert-curated reactions | 2.7.1.169 |
UniProtKB/Swiss-Prot |
|
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UniProtKB/Swiss-Prot entries corresponding to 2.7.1.-
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