ENZYME entry: EC 2.7.1.178

Accepted Name
2-dehydro-3-deoxyglucono/galactono-kinase.
Alternative Name(s)
2-keto-3-deoxy-D-gluconate kinase.
KDG kinase.
Reaction catalysed
ATP + 2-dehydro-3-deoxy-D-gluconate <=> ADP + 2-dehydro-3-deoxy-6-phospho-D-gluconate ATP + 2-dehydro-3-deoxy-D-galactonate <=> ADP + 2-dehydro-3-deoxy-6-phospho-D-galactonate
Comment(s)
The enzyme from the archaeon Sulfolobus solfataricus is involved in glucose and galactose catabolism via the branched variant of the Entner-Doudoroff pathway. It phosphorylates 2-dehydro-3-deoxy-D-gluconate and 2-dehydro-3- deoxy-D-galactonate with similar catalytic efficiency. Cf. EC 2.7.1.45 and EC 2.7.1.58.
Cross-references
BRENDA	2.7.1.178
EC2PDB	2.7.1.178
ExplorEnz	2.7.1.178
PRIAM enzyme-specific profiles	2.7.1.178
KEGG Ligand Database for Enzyme Nomenclature	2.7.1.178
IUBMB Enzyme Nomenclature	2.7.1.178
IntEnz	2.7.1.178
MEDLINE	Find literature relating to 2.7.1.178
MetaCyc	2.7.1.178
UniProtKB/Swiss-Prot	Q97U29, KDGK_SULSO

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