Home  |  Contact
Due to maintenance work, this service and ftp://ftp.expasy.org will be unavailable from Tuesday August 23rd 18:00 until Wednesday August 24th 08:00 CEST. Apologies for the inconvenience.

ENZYME entry: EC

Accepted Name
glycoprotein-mannosyl O(6)-kinase.
Alternative Name(s)
protein O-mannose kinase.
Reaction catalysed
3-O-[beta-D-GalNAc-(1->3)-beta-D-GlcNAc-(1->4)-alpha-D-Man]-L-Thr-[protein] + ATP <=> 3-O-[beta-D-GalNAc-(1->3)-beta-D-GlcNAc-(1->4)-(O-6-P-alpha-D-Man)]-Thr-[protein] + ADP + H(+)
In humans this phosphorylated trisaccharide is attached to an L-threonine residue of alpha-dystroglycan, an extracellular peripheral glycoprotein that acts as a receptor for extracellular matrix proteins containing laminin-G domains, and is important for its activity.
PRIAM enzyme-specific profiles2.7.1.183
KEGG Ligand Database for Enzyme Nomenclature2.7.1.183
IUBMB Enzyme Nomenclature2.7.1.183
MEDLINEFind literature relating to
Rhea expert-curated reactions2.7.1.183
Q5F349, SG196_CHICK;  Q5U3W1, SG196_DANRE;  Q9H5K3, SG196_HUMAN;  
Q95JJ0, SG196_MACFA;  Q3TUA9, SG196_MOUSE;  Q4V8A9, SG196_RAT;  
Q5HZP7, SG196_XENLA;  

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.7.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.7.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-