ID 2.7.1.195 DE protein-N(pi)-phosphohistidine--2-O-alpha-mannosyl-D-glycerate DE phosphotransferase. AN 2-O-alpha-mannosyl-D-glycerate PTS permease. CA (2R)-2-O-(alpha-D-mannosyl)-glycerate(out) + N(pros)-phospho-L-histidyl- CA [protein] = (2R)-2-O-(6-phospho-alpha-D-mannosyl)-glycerate(in) + CA L-histidyl-[protein]. CC -!- This enzyme is a component (known as enzyme II) of a CC phosphoenolpyruvate (PEP)-dependent, sugar transporting CC phosphotransferase system (PTS). CC -!- The system, which is found only in prokaryotes, simultaneously CC transports its substrate from the periplasm or extracellular space CC into the cytoplasm and phosphorylates it. CC -!- The phosphate donor, which is shared among the different systems, CC is a phospho-carrier protein of low molecular mass that has been CC phosphorylated by EC 2.7.3.9. CC -!- Enzyme II, on the other hand, is specific for a particular substrate, CC although in some cases alternative substrates can be transported with CC lower efficiency. CC -!- The reaction involves a successive transfer of the phosphate group to CC several amino acids within the enzyme before the final transfer to CC the substrate. CC -!- Formerly EC 2.7.1.69. DR P54745, MNGA_ECOLI ; //