ID 2.7.1.205 DE protein-N(pi)-phosphohistidine--D-cellobiose phosphotransferase. AN D-cellobiose PTS permease. CA D-cellobiose(out) + N(pros)-phospho-L-histidyl-[protein] = 6-phospho- CA beta-D-glucosyl-(1->4)-D-glucose(in) + L-histidyl-[protein]. CC -!- This enzyme is a component (known as enzyme II) of a CC phosphoenolpyruvate (PEP)-dependent, sugar transporting CC phosphotransferase system (PTS). CC -!- The system, which is found only in prokaryotes, simultaneously CC transports its substrate from the periplasm or extracellular space CC into the cytoplasm and phosphorylates it. CC -!- The phosphate donor, which is shared among the different systems, CC is a phospho-carrier protein of low molecular mass that has been CC phosphorylated by EC 2.7.3.9. CC -!- Enzyme II, on the other hand, is specific for a particular substrate, CC although in some cases alternative substrates can be transported with CC lower efficiency. CC -!- The reaction involves a successive transfer of the phosphate group to CC several amino acids within the enzyme before the final transfer to CC the substrate. CC -!- Formerly EC 2.7.1.69. DR Q9CIF0, PTCB_LACLA ; P55901, PTEB_AERHY ; O05505, PTEB_BACSU ; DR Q45399, PTEB_GEOSE ; //