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ENZYME entry: EC 2.7.1.223

Accepted Name
aminoimidazole riboside kinase.
Reaction catalysed
5-amino-1-(beta-D-ribosyl)imidazole + ATP <=> 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole + ADP + H(+)
Comment(s)
The enzyme, characterized from the bacterium Salmonella enterica, can phosphorylate exogeneously-provided 5-amino-1-(beta-D- ribosyl)imidazole to form 5-amino-1-(5-phospho-beta-D- ribosyl)imidazole (AIR), an important intermediate in the production of both purine mononucleotides and the hydroxymethyl pyrimidine moiety of thiamine.
Cross-references
BRENDA2.7.1.223
EC2PDB2.7.1.223
ExplorEnz2.7.1.223
PRIAM enzyme-specific profiles2.7.1.223
KEGG Ligand Database for Enzyme Nomenclature2.7.1.223
IUBMB Enzyme Nomenclature2.7.1.223
IntEnz2.7.1.223
MEDLINEFind literature relating to 2.7.1.223
MetaCyc2.7.1.223
Rhea expert-curated reactions2.7.1.223
UniProtKB/Swiss-Prot
Q8ZKR2, AIRSK_SALTY

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