ENZYME entry: EC 2.7.1.223
| Accepted Name |
|---|
| Aminoimidazole riboside kinase.
|
| Reaction catalysed |
|---|
| ATP + 5-amino-1-(beta-D-ribosyl)imidazole <=> ADP + 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole |
| Comment(s) |
|---|
| The enzyme, characterized from the bacterium Salmonella enterica,
can phosphorylate exogeneously-provided 5-amino-1-(beta-D-
ribosyl)imidazole to form 5-amino-1-(5-phospho-beta-D-
ribosyl)imidazole (AIR), an important intermediate in the production
of both purine mononucleotides and the hydroxymethyl pyrimidine
moiety of thiamine.
|
| Cross-references |
|---|
| BRENDA | 2.7.1.223 |
| EC2PDB | 2.7.1.223 |
| ExplorEnz | 2.7.1.223 |
| PRIAM enzyme-specific profiles | 2.7.1.223 |
| KEGG Ligand Database for Enzyme Nomenclature | 2.7.1.223 |
| IUBMB Enzyme Nomenclature | 2.7.1.223 |
| IntEnz | 2.7.1.223 |
| MEDLINE | Find literature relating to 2.7.1.223 |
| MetaCyc | 2.7.1.223 |
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