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ENZYME entry: EC 2.7.1.228

Accepted Name
Mannosyl-inositol-phosphoceramide inositolphosphotransferase.
Reaction catalysed
1-phosphatidyl-1D-myo-inositol + a very-long-chain mannosylinositol phospho-(2'R)-2'-hydroxyphytoceramide <=> 1,2-diacyl-sn-glycerol + a very-long-chain mannosyl-diphosphoinositol-(2'R)-2'-hydroxyphytoceramide
Comment(s)
  • This enzyme catalyzes the ultimate reaction in the yeast sphingolipid biosynthesis pathway.
  • It transfers a second phosphoinositol group to mannosyl-inositol- phospho-alpha-hydroxyphytoceramide (MIPC), forming the final and most abundant yeast sphingolipid, mannosyl-diphosphoinositol-ceramide (MIP2C).
Cross-references
BRENDA2.7.1.228
EC2PDB2.7.1.228
ExplorEnz2.7.1.228
PRIAM enzyme-specific profiles2.7.1.228
KEGG Ligand Database for Enzyme Nomenclature2.7.1.228
IUBMB Enzyme Nomenclature2.7.1.228
IntEnz2.7.1.228
MEDLINEFind literature relating to 2.7.1.228
MetaCyc2.7.1.228

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.7.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.7.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-