ENZYME entry: EC 2.7.1.235
Accepted Name | |
---|---|
lipopolysaccharide core heptose(I) kinase | |
Reaction catalysed | |
an L-alpha-D-Hep-(1->3)-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A + ATP <=> ADP + an L-alpha-D-Hep-(1->3)-4-O-phospho-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A + H(+) | |
Comment(s) | |
The enzyme catalyzes the phosphorylation of L-glycero-D-manno-heptose I (the first heptose added to the lipid, Hep I) in the biosynthesis of the inner core oligosaccharide of the lipopolysaccharide (endotoxin) of some Gram-negative bacteria. | |
Cross-references | |
BRENDA | 2.7.1.235 |
EC2PDB | 2.7.1.235 |
ExplorEnz | 2.7.1.235 |
PRIAM enzyme-specific profiles | 2.7.1.235 |
KEGG Ligand Database for Enzyme Nomenclature | 2.7.1.235 |
IUBMB Enzyme Nomenclature | 2.7.1.235 |
IntEnz | 2.7.1.235 |
MEDLINE | Find literature relating to 2.7.1.235 |
MetaCyc | 2.7.1.235 |
Rhea expert-curated reactions | 2.7.1.235 |
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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.7.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.7.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-