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ENZYME

ENZYME entry: EC 2.7.1.48

Accepted Name
uridine/cytidine kinase
Alternative Name(s)
uridine-cytidine kinase
Reaction catalysed
  • ATP + uridine <=> ADP + H(+) + UMP
  • ATP + cytidine <=> ADP + CMP + H(+)
Comment(s)
  • The enzyme, found in prokaryotes and eukaryotes, phosphorylates both uridine and cytidine to their monophosphate forms.
  • The enzyme from Escherichia coli prefers GTP to ATP.
  • The human enzyme also catalyzes the phosphorylation of several cytotoxic ribonucleoside analogs. cf. EC 2.7.1.213.
Cross-references
BRENDA2.7.1.48
EC2PDB2.7.1.48
ExplorEnz2.7.1.48
PRIAM enzyme-specific profiles2.7.1.48
KEGG Ligand Database for Enzyme Nomenclature2.7.1.48
IUBMB Enzyme Nomenclature2.7.1.48
IntEnz2.7.1.48
MEDLINEFind literature relating to 2.7.1.48
MetaCyc2.7.1.48
Rhea expert-curated reactions2.7.1.48
UniProtKB/Swiss-Prot
Q12084, DAS2_YEASTB2BW43, UCK10_BWCOVQ6PA79, UCK1A_XENLA
Q6GPD9, UCK1B_XENLAQ0P5A4, UCK1_BOVINQ66I71, UCK1_DANRE
Q9HA47, UCK1_HUMANQ4R4K2, UCK1_MACFAP52623, UCK1_MOUSE
Q7SYM0, UCK2A_DANREQ7ZV79, UCK2B_DANREQ9BZX2, UCK2_HUMAN
Q99PM9, UCK2_MOUSEQ9QYG8, UCK2_RATB1H116, UCK2_XENTR
Q55EL3, UCKA_DICDIQ8T154, UCKB_DICDIQ54R62, UCKC_DICDI
Q9GNF0, UCKD_DICDIQ9NWZ5, UCKL1_HUMANQ91YL3, UCKL1_MOUSE
Q17413, UCK_CAEELQ9VC99, UCK_DROMEQ9FKS0, UKL1_ARATH
Q9LK34, UKL2_ARATHQ8VYB2, UKL3_ARATHO65583, UKL4_ARATH
Q9LTY6, UKL5_ARATHO74427, URK1_SCHPOP27515, URK1_YEAST
A0KKF8, URK_AERHHA4SML3, URK_AERS4Q5E3Z9, URK_ALIF1
B5FG51, URK_ALIFMB6EIY7, URK_ALISLA6TR08, URK_ALKMQ
B7GIU0, URK_ANOFWC3P969, URK_BACAAC3L5Y6, URK_BACAC
A0RIZ3, URK_BACAHQ81LK8, URK_BACANB7JP70, URK_BACC0
Q730F4, URK_BACC1B7IYN4, URK_BACC2C1ESS5, URK_BACC3
B7HE15, URK_BACC4B7HQD8, URK_BACC7A7GT59, URK_BACCN
B9IYE5, URK_BACCQQ817Z5, URK_BACCRQ634G4, URK_BACCZ
Q6HDE5, URK_BACHKQ65GT3, URK_BACLDA9VI01, URK_BACMK
A8FFL8, URK_BACP2O32033, URK_BACSUA7Z727, URK_BACVZ
Q0SPE9, URK_BORAPQ59190, URK_BORBUB7J0V4, URK_BORBZ
B5RLM3, URK_BORDLQ662Z7, URK_BORGPB2S1K4, URK_BORHD
B5RQJ8, URK_BORRAA1QYG8, URK_BORT9C0ZAS6, URK_BREBN
A9WCC8, URK_CHLAAB8G8N0, URK_CHLADQ9Z7H0, URK_CHLPN
B9LED5, URK_CHLSYC3L140, URK_CLOB6C1FSX6, URK_CLOBJ
B1IJ68, URK_CLOBKA7GGE1, URK_CLOBLB1KXA7, URK_CLOBM
A0Q140, URK_CLONNQ0TPI4, URK_CLOP1Q8XJI6, URK_CLOPE
Q0SS52, URK_CLOPSQ896E3, URK_CLOTEA7MHG8, URK_CROS8
C1CXN1, URK_DEIDVQ9RXZ5, URK_DEIRAP0A8F6, URK_ECO57
P0A8F5, URK_ECOL6P0A8F4, URK_ECOLIA4WCB6, URK_ENT38
B2VFR1, URK_ERWT9B7LV30, URK_ESCF3Q5KWV3, URK_GEOKA
C5D4Y5, URK_GEOSWA4IR72, URK_GEOTNQ7VL27, URK_HAEDU
Q4QP55, URK_HAEI8A5UB17, URK_HAEIEA5UFT8, URK_HAEIG
P44533, URK_HAEINQ9KDD8, URK_HALH5Q9HQC9, URK_HALSA
Q0I2Y9, URK_HISS1B0UT65, URK_HISS2B5XPC8, URK_KLEP3
A6TBG6, URK_KLEP7A8YU29, URK_LACH4Q74KI9, URK_LACJO
Q9CF21, URK_LACLAA2RJB4, URK_LACLMQ02XK6, URK_LACLS
Q88WR0, URK_LACPLQ38VV6, URK_LATSSB1MXP1, URK_LEUCK
Q1WTY6, URK_LIGS1A5VKU8, URK_LIMRDB2G882, URK_LIMRJ
Q92BL6, URK_LISINC1KVE4, URK_LISMCQ71ZH3, URK_LISMF
B8DE13, URK_LISMHQ8Y727, URK_LISMOA0AIU6, URK_LISW6
B9E6Y9, URK_MACCJQ65S71, URK_MANSMP47622, URK_MYCGE
P75217, URK_MYCPNQ8EPT5, URK_OCEIHQ9CM85, URK_PASMU
Q6D7B4, URK_PECASC6DCI6, URK_PECCPQ7N6J4, URK_PHOLL
B4ESY8, URK_PROMHA1SUY9, URK_PSYINB5EXV0, URK_SALA4
Q57MN1, URK_SALCHB5FMU1, URK_SALDCB5R0B5, URK_SALEP
B5RBW3, URK_SALG2B4T9T4, URK_SALHSB4SXV3, URK_SALNS
Q5PDX6, URK_SALPAA9N7M0, URK_SALPBC0Q1G0, URK_SALPC
B5BF73, URK_SALPKB4TNH9, URK_SALSVP67409, URK_SALTI
P67408, URK_SALTYA8GC40, URK_SERP5A1S796, URK_SHEAM
B8E960, URK_SHEB2A3D5E3, URK_SHEB5A6WP54, URK_SHEB8
A9L4F4, URK_SHEB9Q12MJ0, URK_SHEDOQ081H5, URK_SHEFN
B0TJ03, URK_SHEHHQ8EDX4, URK_SHEONA8H3V4, URK_SHEPA
A4Y7K6, URK_SHEPCB8CPI6, URK_SHEPWA0KW26, URK_SHESA
Q0HJN4, URK_SHESMQ0HVY0, URK_SHESRA1RIY2, URK_SHESW
P0A8F7, URK_SHIFLQ2NUC7, URK_SODGMA7X320, URK_STAA1
A6U280, URK_STAA2Q2FGB5, URK_STAA3Q2FXW6, URK_STAA8
A5ITD6, URK_STAA9Q2YT67, URK_STAABQ5HFF1, URK_STAAC
A6QHF2, URK_STAAEP67410, URK_STAAMP67411, URK_STAAN
Q6GG92, URK_STAARQ6G8V8, URK_STAASA8Z4E9, URK_STAAT
P67412, URK_STAAWB9DNJ4, URK_STACTQ5HNT9, URK_STAEQ
Q8CSB2, URK_STAESQ4L6V8, URK_STAHJQ49Y49, URK_STAS1
Q3K1N1, URK_STRA1Q8E5Y5, URK_STRA3Q8E0A8, URK_STRA5
C0M9M0, URK_STRE4B4U220, URK_STREMA8AWT2, URK_STRGC
Q8DTG1, URK_STRMUP67415, URK_STRP1Q04KA9, URK_STRP2
P0DH36, URK_STRP3B5E4U6, URK_STRP4Q5XBI8, URK_STRP6
C1C7H7, URK_STRP7Q8P0F8, URK_STRP8A2RDZ9, URK_STRPG
B1IC10, URK_STRPIB8ZQ77, URK_STRPJP67413, URK_STRPN
P0DH37, URK_STRPQB2IPS2, URK_STRPSB5XM21, URK_STRPZ
P67414, URK_STRR6C0MCM8, URK_STRS7Q5LZ98, URK_STRT1
Q5M3V0, URK_STRT2Q03K46, URK_STRTDB9DSN2, URK_STRU0
C1CEH1, URK_STRZJC1CKV4, URK_STRZPC1CR90, URK_STRZT
Q72L53, URK_THET2Q5SKR5, URK_THET8C4LEX3, URK_TOLAT
B1AIX1, URK_UREP2Q9PQF9, URK_UREPAB5ZBE2, URK_UREU1
B7VLX0, URK_VIBA3A7MVE7, URK_VIBC1Q9KT67, URK_VIBCH
Q87N09, URK_VIBPAQ8D8F4, URK_VIBVUQ7MM12, URK_VIBVY
A1JTX4, URK_YERE8A7FJJ4, URK_YERP3Q1C9T6, URK_YERPA
B2JZK5, URK_YERPBQ8ZFZ9, URK_YERPEA9R2M5, URK_YERPG
Q1CGU6, URK_YERPNA4TKM7, URK_YERPPQ66C70, URK_YERPS
B1JPY6, URK_YERPYQ9UTC5, YIDE_SCHPO

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.7.1.-
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