A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.
ENZYME entry: EC 2.7.11.18
| Accepted Name |
|---|
| [Myosin light-chain] kinase.
|
| Alternative Name(s) |
|---|
| [Myosin-light-chain] kinase. |
| Calcium/calmodulin-dependent myosin light chain kinase. |
| MLCK. |
| MLCkase. |
| Myosin kinase. |
| Myosin light chain kinase. |
| Myosin light chain protein kinase. |
| Myosin light-chain kinase. |
| Myosin light-chain kinase (phosphorylating). |
| Smooth-muscle-myosin-light-chain kinase. |
| Reaction catalysed |
|---|
| ATP + [myosin light-chain] <=> ADP + [myosin light-chain] phosphate |
| Cofactor(s) |
|---|
| Ca(2+).
|
| Comment(s) |
|---|
- Requires calmodulin for activity.
- The 20 kDa light chain from smooth muscle myosin is phosphorylated
more rapidly than any other acceptor, but light chains from other
myosins and myosin itself can act as acceptors, more slowly.
- Formerly EC 2.7.1.117.
|
| Cross-references |
|---|
| PROSITE | PDOC00100 |
| BRENDA | 2.7.11.18 |
| EC2PDB | 2.7.11.18 |
| ExplorEnz | 2.7.11.18 |
| PRIAM enzyme-specific profiles | 2.7.11.18 |
| KEGG Ligand Database for Enzyme Nomenclature | 2.7.11.18 |
| IUBMB Enzyme Nomenclature | 2.7.11.18 |
| IntEnz | 2.7.11.18 |
| MEDLINE | Find literature relating to 2.7.11.18 |
| MetaCyc | 2.7.11.18 |
| UniProtKB/Swiss-Prot |
| A4IFM7, MYLK2_BOVIN; | Q9H1R3, MYLK2_HUMAN; | Q8VCR8, MYLK2_MOUSE; |
| P07313, MYLK2_RABIT; | P20689, MYLK2_RAT; | A8C984, MYLK3_DANRE; |
| Q32MK0, MYLK3_HUMAN; | Q3UIZ8, MYLK3_MOUSE; | Q5RDG7, MYLK3_PONAB; |
| E9PT87, MYLK3_RAT; | P25323, MYLKA_DICDI; | Q86AD7, MYLKB_DICDI; |
| Q54SJ5, MYLKC_DICDI; | Q54CY9, MYLKD_DICDI; | Q54PB4, MYLKE_DICDI; |
| Q54W86, MYLKF_DICDI; | Q869W6, MYLKG_DICDI; | Q28824, MYLK_BOVIN; |
| P11799, MYLK_CHICK; | Q15746, MYLK_HUMAN; | Q6PDN3, MYLK_MOUSE; |
| P79280, MYLK_PIG; | P29294, MYLK_RABIT; | O02827, MYLK_SHEEP; |
|
View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot
entries referenced
in this entry, with possibility to download in different formats, align etc.
All
ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 2.7.11.-
All
ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 2.7.-.-
All
ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-