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ENZYME

ENZYME entry: EC 2.7.11.20

PURL: https://purl.expasy.org/enzyme/EC/2.7.11.20
Accepted Name
[elongation factor 2] kinase
Alternative Name(s)
Ca/CaM-kinase III
calmodulin-dependent protein kinase III
CaM kinase III
eEF2K
eEF2 kinase
EF2K
Reaction catalysed
[translation elongation factor 2] + ATP = [translation elongation factor 2]-phosphate + ADP + H(+)
Comment(s)
  • Requires calmodulin for activity.
  • Can also be phosphorylated by the catalytic subunit of EC 2.7.11.11.
  • Elongation factor 2 is phosphorylated in several cell types in response to various growth factors, hormones and other stimuli that raise intracellular Ca(2+).
Cross-references
BRENDA2.7.11.20
EC2PDB2.7.11.20
ExplorEnz2.7.11.20
KEGG Ligand Database for Enzyme Nomenclature2.7.11.20
IUBMB Enzyme Nomenclature2.7.11.20
MEDLINEFind literature relating to 2.7.11.20
MetaCyc2.7.11.20
Rhea expert-curated reactions2.7.11.20
UniProtKB/Swiss-Prot
O01991, EF2K_CAEELO00418, EF2K_HUMANO08796, EF2K_MOUSE
P70531, EF2K_RAT

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.7.11.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.7.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-