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ENZYME

ENZYME entry: EC 2.7.11.23

Accepted Name
[RNA-polymerase]-subunit kinase
Alternative Name(s)
CTD kinase
Reaction catalysed
[DNA-directed RNA polymerase] + ATP <=> ADP + H(+) + phospho-[DNA-directed RNA polymerase]
Comment(s)
  • Appears to be distinct from other protein phosphokinases.
  • Brings about multiple phosphorylation of the unique C-terminal repeat domain of the largest subunit of eukaryotic EC 2.7.7.6.
  • Does not phosphorylate casein, phosvitin or histone.
  • Formerly EC 2.7.1.141.
Cross-references
BRENDA2.7.11.23
EC2PDB2.7.11.23
ExplorEnz2.7.11.23
PRIAM enzyme-specific profiles2.7.11.23
KEGG Ligand Database for Enzyme Nomenclature2.7.11.23
IUBMB Enzyme Nomenclature2.7.11.23
IntEnz2.7.11.23
MEDLINEFind literature relating to 2.7.11.23
MetaCyc2.7.11.23
Rhea expert-curated reactions2.7.11.23
UniProtKB/Swiss-Prot
Q75D46, BUR1_ASHGOQ4WTN5, BUR1_ASPFUQ9Y7W4, BUR1_CANAL
Q6FQ83, BUR1_CANGBQ6BV06, BUR1_DEBHAQ96VK3, BUR1_EMENI
Q4I5U9, BUR1_GIBZEQ6CRA9, BUR1_KLULCQ871M9, BUR1_NEUCR
Q6C842, BUR1_YARLIP23293, BUR1_YEASTP24923, CDC21_MEDSA
P19026, CDC21_PEAP28567, CDC22_PEAQ38772, CDC2A_ANTMA
Q38773, CDC2B_ANTMAQ38774, CDC2C_ANTMAQ38775, CDC2D_ANTMA
P23111, CDC2_MAIZEP93101, CDC2_OXYRBP43290, CDC2_PETHY
Q41639, CDC2_VIGACP52389, CDC2_VIGUND2H526, CDK12_AILME
E1BB50, CDK12_BOVINP46551, CDK12_CAEELQ9VP22, CDK12_DROME
Q9NYV4, CDK12_HUMANQ14AX6, CDK12_MOUSEQ3MJK5, CDK12_RAT
B5DE93, CDK12_XENTRE1BB52, CDK13_BOVINQ14004, CDK13_HUMAN
Q69ZA1, CDK13_MOUSEP35567, CDK1A_XENLAP24033, CDK1B_XENLA
P48734, CDK1_BOVINA8XA58, CDK1_CAEBRP34556, CDK1_CAEEL
P51958, CDK1_CARAUP13863, CDK1_CHICKP34112, CDK1_DICDI
P23572, CDK1_DROMEP06493, CDK1_HUMANP11440, CDK1_MOUSE
Q9DGA5, CDK1_ORYCUQ9DGA2, CDK1_ORYJAQ9DGD3, CDK1_ORYLA
Q9DG98, CDK1_ORYLUQ5RCH1, CDK1_PONABQ9W739, CDK1_RANDY
P39951, CDK1_RATQ01917, CDK2H_CRIFAQ4Z6R1, CDK2H_PLABA
Q4Y4B1, CDK2H_PLACHP61075, CDK2H_PLAF7Q07785, CDK2H_PLAFK
O96821, CDK2H_PLAKHQ9XZD6, CDK2H_PLAVIQ7RM49, CDK2H_PLAYO
Q26671, CDK2H_THEANQ27032, CDK2H_THEPAP23573, CDK2_DROME
G5EFV5, CDK7_CAEELP51953, CDK7_CARAUP54685, CDK7_DICDI
P50613, CDK7_HUMANQ03147, CDK7_MOUSEP51952, CDK7_RAT
P20911, CDK7_XENLAQ17IE8, CDK8_AEDAEP0C661, CDK8_CAEBR
P90866, CDK8_CAEELQ8JH47, CDK8_DANREQ95YH0, CDK8_DICDI
Q9VT57, CDK8_DROMEP49336, CDK8_HUMANQ8R3L8, CDK8_MOUSE
Q66KH9, CDK8_XENLAQ6P3N6, CDK8_XENTRQ4V862, CDK9A_XENLA
Q7ZX42, CDK9B_XENLAQ5EAB2, CDK9_BOVINQ9TVL3, CDK9_CAEEL
Q5ZKN1, CDK9_CHICKQ7SXE8, CDK9_DANREP50750, CDK9_HUMAN
Q99J95, CDK9_MOUSEQ641Z4, CDK9_RATQ96WV9, CDK9_SCHPO
Q6GLD8, CDK9_XENTRP24100, CDKA1_ARATHP29618, CDKA1_ORYSJ
P29619, CDKA2_ORYSJQ9LFT8, CDKC1_ARATHQ6I5Y0, CDKC1_ORYSJ
Q8W4P1, CDKC2_ARATHQ5JK68, CDKC2_ORYSJQ6ZAG3, CDKC3_ORYSJ
Q9C9U2, CDKD1_ARATHA2Y4B6, CDKD1_ORYSIP29620, CDKD1_ORYSJ
Q9C9M7, CDKD2_ARATHQ9LMT0, CDKD3_ARATHQ84TI6, CDKE1_ARATH
Q336M2, CDKE1_ORYSJO80345, CDKF1_ARATHA2YCH5, CDKF1_ORYSI
Q5Z754, CDKF1_ORYSJQ2QSL4, CDKF2_ORYSJQ84SN3, CDKF3_ORYSJ
Q6Z8C8, CDKF4_ORYSJA2X6X1, CDKG1_ORYSIQ6K5F8, CDKG1_ORYSJ
A2XUW1, CDKG2_ORYSIQ7XUF4, CDKG2_ORYSJP25859, CKB11_ARATH
Q8L4P8, CKB11_ORYSJQ2V419, CKB12_ARATHQ8LF80, CKB21_ARATH
Q0J4I1, CKB21_ORYSJQ8LG64, CKB22_ARATHQ06309, CRK1_LEIME
Q12126, CRK1_SCHPOQ8SQW2, CTK1_ENCCUO14098, CTK1_SCHPO
Q03957, CTK1_YEASTQ13627, DYR1A_HUMANQ61214, DYR1A_MOUSE
P85051, DYR1A_RABITQ63470, DYR1A_RATQ2TAE3, DYR1A_XENLA
Q0IJ08, DYR1A_XENTRQ8SW92, KIN28_ENCCUP06242, KIN28_YEAST
Q751F5, SSN3_ASHGOA1CL96, SSN3_ASPCLQ4WYR6, SSN3_ASPFU
A2QU77, SSN3_ASPNCQ2UC58, SSN3_ASPORQ0CQK1, SSN3_ASPTN
Q5AHK2, SSN3_CANALQ6FKC6, SSN3_CANGBQ2GYV9, SSN3_CHAGB
Q1EBK0, SSN3_COCIMP0CS77, SSN3_CRYNBP0CS76, SSN3_CRYNJ
Q6BM25, SSN3_DEBHAQ5BAE1, SSN3_EMENIQ4FCZ5, SSN3_GIBMO
Q6CR51, SSN3_KLULCA4QXX4, SSN3_MAGO7A1D624, SSN3_NEOFI
Q0TWJ7, SSN3_PHANOA3LUB9, SSN3_PICSTO13958, SSN3_SCHPO
Q4P9T2, SSN3_USTMAQ6CCB0, SSN3_YARLIP39073, SSN3_YEAST

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.7.11.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.7.-.-
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