ID   2.7.11.26
DE   [tau protein] kinase.
AN   [tau-protein] kinase.
AN   glycogen synthase kinase-3beta.
AN   GSK.
AN   protein tau kinase.
AN   tau kinase.
AN   tau-tubulin kinase.
AN   TPK.
AN   TTK.
CA   (1) ATP + L-seryl-[tau protein] = ADP + H(+) + O-phospho-L-seryl-[tau
CA   protein].
CA   (2) ATP + L-threonyl-[tau protein] = ADP + H(+) + O-phospho-L-threonyl-
CA   [tau protein].
CC   -!- Activated by tubulin.
CC   -!- Involved in the formation of paired helical filaments, which are the
CC       main fibrous component of all fibrillary lesions in brain and are
CC       associated with Alzheimer's disease.
CC   -!- Formerly EC 2.7.1.135.
DR   Q13131, AAPK1_HUMAN;  Q5EG47, AAPK1_MOUSE;  Q09136, AAPK1_PIG  ;
DR   Q5RDH5, AAPK1_PONAB;  P54645, AAPK1_RAT  ;  Q8TDC3, BRSK1_HUMAN;
DR   Q5RJI5, BRSK1_MOUSE;  B2DD29, BRSK1_RAT  ;  Q8IWQ3, BRSK2_HUMAN;
DR   Q69Z98, BRSK2_MOUSE;  D3ZML2, BRSK2_RAT  ;  Q55C57, GLKA_DICDI ;
DR   P49840, GSK3A_HUMAN;  Q2NL51, GSK3A_MOUSE;  P18265, GSK3A_RAT  ;
DR   P49841, GSK3B_HUMAN;  Q9WV60, GSK3B_MOUSE;  P18266, GSK3B_RAT  ;
DR   Q5YJC2, GSK3B_SPECI;  Q388M1, GSK3B_TRYB2;  Q91757, GSK3B_XENLA;
DR   P83101, GSK3H_DROME;  A8X5H5, GSK3_CAEBR ;  Q9U2Q9, GSK3_CAEEL ;
DR   P51136, GSK3_DICDI ;  P35508, KC1D_BOVIN ;  P48730, KC1D_HUMAN ;
DR   Q9DC28, KC1D_MOUSE ;  Q5RC72, KC1D_PONAB ;  P81123, KC1D_RABIT ;
DR   Q06486, KC1D_RAT   ;  Q5BP74, KC1D_XENLA ;  Q6P647, KC1D_XENTR ;
DR   Q9P0L2, MARK1_HUMAN;  Q8VHJ5, MARK1_MOUSE;  O08678, MARK1_RAT  ;
DR   Q7KZI7, MARK2_HUMAN;  Q05512, MARK2_MOUSE;  O08679, MARK2_RAT  ;
DR   Q16816, PHKG1_HUMAN;  P07934, PHKG1_MOUSE;  P00518, PHKG1_RABIT;
DR   P13286, PHKG1_RAT  ;
//