ENZYME

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A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC 2.7.11.29

Accepted Name
[Low-density-lipoprotein receptor] kinase.
Alternative Name(s)
LDL receptor kinase.
Low-density lipoprotein receptor kinase.
Low-density-lipoprotein kinase.
Low-density-lipoprotein receptor kinase (phosphorylating).
Reaction catalysed
ATP + [low-density-lipoprotein receptor]-L-serine <=> ADP + [low-density-lipoprotein receptor]-O-phospho-L-serine
Comment(s)
Phosphorylates the last serine residue (Ser-833) in the cytoplasmic domain of the low-density lipoprotein receptor. Casein can also act as a substrate but with lower affinity. GTP can act instead of ATP. Formerly EC 2.7.1.131.
Cross-references
BRENDA	2.7.11.29
EC2PDB	2.7.11.29
ExplorEnz	2.7.11.29
PRIAM enzyme-specific profiles	2.7.11.29
KEGG Ligand Database for Enzyme Nomenclature	2.7.11.29
IUBMB Enzyme Nomenclature	2.7.11.29
IntEnz	2.7.11.29
MEDLINE	Find literature relating to 2.7.11.29
MetaCyc	2.7.11.29

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