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ENZYME

ENZYME entry: EC 2.7.11.29

PURL: https://purl.expasy.org/enzyme/EC/2.7.11.29
Accepted Name
[low-density-lipoprotein receptor] kinase
Alternative Name(s)
LDL receptor kinase
low-density-lipoprotein kinase
low-density lipoprotein receptor kinase
low-density-lipoprotein receptor kinase (phosphorylating)
Reaction catalysed
L-seryl-[low-density-lipoprotein receptor] + ATP = O-phospho-L-seryl-[low-density-lipoprotein receptor] + ADP + H(+)
Comment(s)
  • Phosphorylates the last serine residue (Ser-833) in the cytoplasmic domain of the low-density lipoprotein receptor.
  • Casein can also act as a substrate but with lower affinity.
  • GTP can act instead of ATP.
  • Formerly EC 2.7.1.131.
Cross-references
BRENDA2.7.11.29
EC2PDB2.7.11.29
ExplorEnz2.7.11.29
KEGG Ligand Database for Enzyme Nomenclature2.7.11.29
IUBMB Enzyme Nomenclature2.7.11.29
MEDLINEFind literature relating to 2.7.11.29
MetaCyc2.7.11.29
Rhea expert-curated reactions2.7.11.29

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.7.11.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.7.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-