ID   2.7.11.31
DE   [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase.
AN   [hydroxymethylglutaryl-CoA reductase (NADPH2)] kinase.
AN   3-hydroxy-3-methylglutaryl-CoA reductase kinase.
AN   3-hydroxy-3-methylglutaryl coenzyme A reductase kinase.
AN   AMP-activated protein kinase.
AN   AMPK.
AN   beta-hydroxy-beta-methylglutaryl-CoA reductase kinase.
AN   HMG-CoA reductase kinase.
AN   hydroxymethylglutaryl-CoA reductase kinase.
AN   hydroxymethylglutaryl coenzyme A reductase kinase.
AN   hydroxymethylglutaryl coenzyme A reductase kinase (phosphorylating).
AN   reductase kinase.
CA   ATP + L-seryl-[3-hydroxy-3-methylglutaryl-coenzyme A reductase] = ADP +
CA   H(+) + O-phospho-L-seryl-[3-hydroxy-3-methylglutaryl-coenzyme A
CA   reductase].
CC   -!- Activated by AMP.
CC   -!- EC 1.1.1.34 is inactivated by the phosphorylation of the enzyme
CC       protein.
CC   -!- Histones can also act as acceptors.
CC   -!- Can also phosphorylate EC 6.4.1.2 and EC 3.1.1.79.
CC   -!- Thr-172 within the catalytic subunit (alpha-subunit) is the major
CC       site phosphorylated by the AMP-activated protein kinase kinase.
CC   -!- GTP can act instead of ATP.
CC   -!- Formerly EC 2.7.1.109 and EC 2.7.11.27.
DR   Q13131, AAPK1_HUMAN;  Q5EG47, AAPK1_MOUSE;  Q09136, AAPK1_PIG  ;
DR   Q5RDH5, AAPK1_PONAB;  P54645, AAPK1_RAT  ;  P54646, AAPK2_HUMAN;
DR   Q8BRK8, AAPK2_MOUSE;  Q28948, AAPK2_PIG  ;  Q5RD00, AAPK2_PONAB;
DR   Q09137, AAPK2_RAT  ;
//