A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_09. Read more about EC 7 here.
ENZYME entry: EC 2.7.11.8
| Accepted Name |
|---|
| Fas-activated serine/threonine kinase.
|
| Alternative Name(s) |
|---|
| FAST. |
| FASTK. |
| Reaction catalysed |
|---|
| ATP + [Fas-activated serine/threonine protein] <=> ADP + [Fas-activated serine/threonine phosphoprotein] |
| Comment(s) |
|---|
- This enzyme is activated during Fas-mediated apoptosis.
- Following Fas ligation, the enzyme, which is constitutively
phosphorylated, is dephosphorylated, and it is the dephosphorylated
form that causes phosphorylation of TIA-1, a nuclear RNA-binding
protein.
- Phosphorylation of TIA-1 precedes the onset of DNA fragmentation.
- Formerly EC 2.7.1.37.
|
| Cross-references |
|---|
| BRENDA | 2.7.11.8 |
| EC2PDB | 2.7.11.8 |
| ExplorEnz | 2.7.11.8 |
| PRIAM enzyme-specific profiles | 2.7.11.8 |
| KEGG Ligand Database for Enzyme Nomenclature | 2.7.11.8 |
| IUBMB Enzyme Nomenclature | 2.7.11.8 |
| IntEnz | 2.7.11.8 |
| MEDLINE | Find literature relating to 2.7.11.8 |
| MetaCyc | 2.7.11.8 |
| UniProtKB/Swiss-Prot |
|
View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot
entries referenced
in this entry, with possibility to download in different formats, align etc.
All
ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 2.7.11.-
All
ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 2.7.-.-
All
ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-