Home  |  Contact

ENZYME entry: EC 2.7.4.21

Accepted Name
inositol-hexakisphosphate 5-kinase.
Alternative Name(s)
inositol-hexakisphosphate kinase.
IP6K.
Reaction catalysed
  • 1D-myo-inositol hexakisphosphate + ATP <=> 5-diphospho-1D-myo-inositol 1,2,3,4,6-pentakisphosphate + ADP
  • 1-diphospho-myo-inositol 2,3,4,5,6-pentakisphosphate + ATP + H(+) <=> 1,5-bis(diphospho)-1D-myo-inositol 2,3,4,6-tetrakisphosphate + ADP
Comment(s)
  • Three mammalian isoforms are known to exist.
  • Formerly EC 2.7.1.152.
Cross-references
BRENDA2.7.4.21
EC2PDB2.7.4.21
ExplorEnz2.7.4.21
PRIAM enzyme-specific profiles2.7.4.21
KEGG Ligand Database for Enzyme Nomenclature2.7.4.21
IUBMB Enzyme Nomenclature2.7.4.21
IntEnz2.7.4.21
MEDLINEFind literature relating to 2.7.4.21
MetaCyc2.7.4.21
Rhea expert-curated reactions2.7.4.21
UniProtKB/Swiss-Prot
Q92551, IP6K1_HUMAN;  Q6PD10, IP6K1_MOUSE;  Q9ESM0, IP6K1_RAT;  
Q96PC2, IP6K3_HUMAN;  Q8BWD2, IP6K3_MOUSE;  Q12494, KCS1_YEAST;  

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.7.4.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.7.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-