A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC 2.7.4.23

Accepted Name
Ribose 1,5-bisphosphate phosphokinase.
Alternative Name(s)
Ribose 1,5-bisphosphokinase.
Reaction catalysed
ATP + alpha-D-ribose 1,5-bisphosphate <=> ADP + 5-phospho-alpha-D-ribose 1-diphosphate
Comment(s)
  • This enzyme, found in NAD suppression mutants of Escherichia coli, synthesizes 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) without the participation of EC 2.7.6.1.
  • Ribose, ribose 1-phosphate and ribose 5-phosphate are not substrates, and GTP cannot act as a phosphate donor.
Cross-references
BRENDA2.7.4.23
EC2PDB2.7.4.23
ExplorEnz2.7.4.23
PRIAM enzyme-specific profiles2.7.4.23
KEGG Ligand Database for Enzyme Nomenclature2.7.4.23
IUBMB Enzyme Nomenclature2.7.4.23
IntEnz2.7.4.23
MEDLINEFind literature relating to 2.7.4.23
MetaCyc2.7.4.23
UniProtKB/Swiss-Prot
E3HQ85, PHNN_ACHXA;  A5G2M7, PHNN_ACICJ;  A9CKM5, PHNN_AGRFC;  
C1DLT0, PHNN_AZOVD;  Q89V30, PHNN_BRADU;  Q57D38, PHNN_BRUAB;  
C0RJ73, PHNN_BRUMB;  A1V0B1, PHNN_BURMS;  Q63R14, PHNN_BURPS;  
Q11C47, PHNN_CHESB;  Q7NWY0, PHNN_CHRVO;  C7LNQ3, PHNN_DESBD;  
D2C357, PHNN_DICZ5;  Q8X5P4, PHNN_ECO57;  P16690, PHNN_ECOLI;  
B1LPR3, PHNN_ECOSM;  E3G1M3, PHNN_ENTLS;  E3J0E1, PHNN_FRAIE;  
A6SU94, PHNN_JANMA;  A6TH13, PHNN_KLEP7;  C1D7Y5, PHNN_LARHH;  
B1LY53, PHNN_METRJ;  E1SHE4, PHNN_PANVC;  Q6D9W6, PHNN_PECAS;  
D0KG93, PHNN_PECPW;  A6V255, PHNN_PSEA7;  C3K5M3, PHNN_PSEFS;  
A1T0U7, PHNN_PSYIN;  B3PXI8, PHNN_RHIE6;  Q6NBY8, PHNN_RHOPA;  
Q1GL02, PHNN_RUEST;  A9MGI9, PHNN_SALAR;  Q329H3, PHNN_SHIDS;  
Q3SGK8, PHNN_THIDA;  Q7CKG8, PHNN_YERPE;  A8IA58, RBKTP_AZOC5;  
Q0K3R9, RBKTP_CUPNH;  Q46UT0, RBKTP_CUPNJ;  B2AIF3, RBKTP_CUPTR;  
Q16A32, RBKTP_ROSDO;  

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All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.7.4.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.7.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-