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ENZYME entry: EC 2.7.4.34

Accepted Name
GDP-polyphosphate phosphotransferase.
Alternative Name(s)
polyphosphate kinase 2.
Reaction catalysed
[phosphate](n) + GTP <=> [phosphate](n+1) + GDP
Comment(s)
  • Polyphosphate kinase 2, characterized from the bacterium Pseudomonas aeruginosa, uses inorganic polyphosphate as a donor to convert GDP to GTP.
  • The enzyme can also act on ADP (cf. EC 2.7.4.1), but with lower activity.
  • The enzyme has only a trivial activity in the opposite direction (synthesizing polyphosphate from GTP).
  • The GTP that is produced is believed to be consumed by EC 2.7.7.13.
Cross-references
BRENDA2.7.4.34
EC2PDB2.7.4.34
ExplorEnz2.7.4.34
PRIAM enzyme-specific profiles2.7.4.34
KEGG Ligand Database for Enzyme Nomenclature2.7.4.34
IUBMB Enzyme Nomenclature2.7.4.34
IntEnz2.7.4.34
MEDLINEFind literature relating to 2.7.4.34
MetaCyc2.7.4.34
Rhea expert-curated reactions2.7.4.34
UniProtKB/Swiss-Prot
Q9I6Z1, PK21A_PSEAE

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