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A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC

Accepted Name
Nucleoside-triphosphate-aldose-1-phosphate nucleotidyltransferase.
Alternative Name(s)
GDP hexose pyrophosphorylase.
GTP:alpha-D-hexose-1-phosphate guanylyltransferase.
Guanosine diphosphohexose pyrophosphorylase.
Hexose 1-phosphate nucleotidyltransferase.
Hexose nucleotidylating enzyme.
Hexose-1-phosphate guanylyltransferase.
NDP-hexose diphosphorylase.
NDP-hexose pyrophosphorylase.
NTP:hexose-1-phosphate nucleotidyltransferase.
Nucleoside diphosphohexose pyrophosphorylase.
Nucleoside-triphosphate-hexose-1-phosphate nucleotidyltransferase.
Reaction catalysed
Nucleoside triphosphate + alpha-D-aldose 1-phosphate <=> diphosphate + NDP-hexose
  • In decreasing order of activity, guanosine, inosine and adenosine diphosphate hexoses are substrates in the reverse reaction, with either glucose or mannose as the sugar.
  • Formerly EC
PRIAM enzyme-specific profiles2.7.7.28
KEGG Ligand Database for Enzyme Nomenclature2.7.7.28
IUBMB Enzyme Nomenclature2.7.7.28
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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.7.7.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.7.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-