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ENZYME

ENZYME entry: EC 2.7.7.31

Accepted Name
DNA nucleotidylexotransferase
Alternative Name(s)
terminal addition enzyme
terminal deoxynucleotidyltransferase
terminal deoxyribonucleotidyltransferase
terminal transferase
Reaction catalysed
a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)
Comment(s)
  • Catalyzes template-independent extension of the 3'-end of a DNA strand by one nucleotide at a time.
  • Cannot initiate a chain de novo.
  • Nucleoside may be ribo- or deoxyribo-.
Cross-references
BRENDA2.7.7.31
EC2PDB2.7.7.31
ExplorEnz2.7.7.31
PRIAM enzyme-specific profiles2.7.7.31
KEGG Ligand Database for Enzyme Nomenclature2.7.7.31
IUBMB Enzyme Nomenclature2.7.7.31
IntEnz2.7.7.31
MEDLINEFind literature relating to 2.7.7.31
MetaCyc2.7.7.31
Rhea expert-curated reactions2.7.7.31
UniProtKB/Swiss-Prot
O54003, REP75_PYRABO57486, TDT_AMBMEP06526, TDT_BOVIN
P36195, TDT_CHICKA4PCD4, TDT_EULMAP04053, TDT_HUMAN
O02789, TDT_MONDOP09838, TDT_MOUSEQ92089, TDT_ONCMY
P42118, TDT_XENLA

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.7.7.-
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