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ENZYME entry: EC 2.7.7.67

Accepted Name
CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol synthase.
Alternative Name(s)
CDP-2,3-bis-O-(geranylgeranyl)-sn-glycerol synthase.
CDP-archaeol synthase.
CDP-unsaturated archaeol synthase.
Reaction catalysed
CTP + 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate <=> diphosphate + CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol
Cofactor(s)
K(+); Mg(2+).
Comment(s)
  • Catalyzes one of the steps in the biosynthesis of polar lipids in archaea, which are characterized by having an sn-glycero-1-phosphate backbone rather than an sn-glycero-3-phosphate backbone as is found in bacteria and eukaryotes.
  • Formerly EC 2.7.7.n2.
Cross-references
BRENDA2.7.7.67
EC2PDB2.7.7.67
ExplorEnz2.7.7.67
PRIAM enzyme-specific profiles2.7.7.67
KEGG Ligand Database for Enzyme Nomenclature2.7.7.67
IUBMB Enzyme Nomenclature2.7.7.67
IntEnz2.7.7.67
MEDLINEFind literature relating to 2.7.7.67
MetaCyc2.7.7.67
Rhea expert-curated reactions2.7.7.67
UniProtKB/Swiss-Prot
Q9YF05, CDPAS_AERPE;  O28534, CDPAS_ARCFU;  B9LSA9, CDPAS_HALLT;  
Q5UY54, CDPAS_HALMA;  B0R737, CDPAS_HALS3;  Q9HNG1, CDPAS_HALSA;  
Q18FD0, CDPAS_HALWD;  A2BN92, CDPAS_HYPBU;  A6UWB6, CDPAS_META3;  
Q8TKT8, CDPAS_METAC;  Q0W6Q1, CDPAS_METAR;  A7I6J9, CDPAS_METB6;  
Q465Q6, CDPAS_METBF;  Q12X42, CDPAS_METBU;  Q2FLB3, CDPAS_METHJ;  
Q58995, CDPAS_METJA;  Q8TWG2, CDPAS_METKA;  A2SQ88, CDPAS_METLZ;  
A4G0M1, CDPAS_METM5;  A9A8W5, CDPAS_METM6;  A6VHW4, CDPAS_METM7;  
Q8Q0J5, CDPAS_METMA;  A3CU85, CDPAS_METMJ;  Q6LWL1, CDPAS_METMP;  
B8GEE2, CDPAS_METPE;  Q2NHB7, CDPAS_METST;  O26920, CDPAS_METTH;  
A0B8Y7, CDPAS_METTP;  A6UQY1, CDPAS_METVS;  Q3ITE8, CDPAS_NATPD;  
Q6L013, CDPAS_PICTO;  Q9UY86, CDPAS_PYRAB;  Q8ZYR4, CDPAS_PYRAE;  
A4WN93, CDPAS_PYRAR;  A3MXY4, CDPAS_PYRCJ;  Q8U3Q8, CDPAS_PYRFU;  
O58081, CDPAS_PYRHO;  A1RSF4, CDPAS_PYRIL;  Q9UXG3, CDPAS_SACS2;  
A3DM64, CDPAS_STAMF;  Q4JAC0, CDPAS_SULAC;  C3N5M2, CDPAS_SULIA;  
C4KH98, CDPAS_SULIK;  C3MQ04, CDPAS_SULIL;  C3MVC3, CDPAS_SULIM;  
C3NHG3, CDPAS_SULIN;  C3NE86, CDPAS_SULIY;  Q975E2, CDPAS_SULTO;  
Q9HLW7, CDPAS_THEAC;  C5A2X0, CDPAS_THEGJ;  Q5JEX0, CDPAS_THEKO;  
B6YUC9, CDPAS_THEON;  A1RXB2, CDPAS_THEPD;  Q97CB5, CDPAS_THEVO;  

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