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ENZYME

ENZYME entry: EC 2.7.7.68

Accepted Name
2-phospho-L-lactate guanylyltransferase
Reaction catalysed
(2S)-2-phospholactate + GTP + H(+) = (2S)-lactyl-2-diphospho-5'-guanosine + diphosphate
Comment(s)
This enzyme is involved in the biosynthesis of coenzyme F420, a redox-active cofactor, in all methanogenic archaea. cf. EC 2.7.7.105 and EC 2.7.7.106.
Cross-references
BRENDA2.7.7.68
EC2PDB2.7.7.68
ExplorEnz2.7.7.68
PRIAM enzyme-specific profiles2.7.7.68
KEGG Ligand Database for Enzyme Nomenclature2.7.7.68
IUBMB Enzyme Nomenclature2.7.7.68
IntEnz2.7.7.68
MEDLINEFind literature relating to 2.7.7.68
MetaCyc2.7.7.68
Rhea expert-curated reactions2.7.7.68
UniProtKB/Swiss-Prot
O28218, COFC_ARCFUD2RFQ5, COFC_ARCPAD3RZQ1, COFC_FERPA
B9LQ33, COFC_HALLTQ5UXM7, COFC_HALMAC7P363, COFC_HALMD
B0R6P7, COFC_HALS3Q9HNV0, COFC_HALSAD2RWE9, COFC_HALTV
C7NN78, COFC_HALUDD4GVD5, COFC_HALVDQ18FK8, COFC_HALWD
A6UUS0, COFC_META3Q8TQQ2, COFC_METACQ0W6V1, COFC_METAR
A7IAF1, COFC_METB6Q466A1, COFC_METBFQ12WF3, COFC_METBU
C7P592, COFC_METFAQ2FQJ1, COFC_METHJD5VSX2, COFC_METIM
Q58297, COFC_METJAQ8TXS3, COFC_METKAA2ST69, COFC_METLZ
A4G074, COFC_METM5A9A8H9, COFC_METM6A6VIA6, COFC_METM7
Q8PU52, COFC_METMAA3CWL3, COFC_METMJQ6M101, COFC_METMP
D5E7G9, COFC_METMSB8GKC0, COFC_METPED1Z1G0, COFC_METPS
D3E2P3, COFC_METRMA5UJW5, COFC_METS3D3S534, COFC_METSF
Q2NFK9, COFC_METSTO26710, COFC_METTHA0B5I5, COFC_METTP
C9REF5, COFC_METVMA6URA0, COFC_METVSD3SYZ8, COFC_NATMM
Q3IRF2, COFC_NATPD

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.7.7.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.7.-.-
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