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ENZYME

ENZYME entry: EC 2.7.7.85

PURL: https://purl.expasy.org/enzyme/EC/2.7.7.85
Accepted Name
diadenylate cyclase
Alternative Name(s)
cyclic-di-AMP synthase
Reaction catalysed
2 ATP = 3',3'-c-di-AMP + 2 diphosphate
Comment(s)
  • Cyclic di-3',5'-adenylate is a bioactive molecule produced by some bacteria and archaea, which may function as a secondary signaling molecule.
  • The intracellular bacterial pathogen Listeria monocytogenes secretes it into the host's cytosol, where it triggers a cytosolic pathway of innate immunity.
Cross-references
BRENDA2.7.7.85
EC2PDB2.7.7.85
ExplorEnz2.7.7.85
KEGG Ligand Database for Enzyme Nomenclature2.7.7.85
IUBMB Enzyme Nomenclature2.7.7.85
MEDLINEFind literature relating to 2.7.7.85
MetaCyc2.7.7.85
Rhea expert-curated reactions2.7.7.85
UniProtKB/Swiss-Prot
Q45589, CDAA_BACSUO31854, CDAS_BACSUD5TM67, CDAS_BACT1
P0DXA3, CDNB_ESCALD7Y2H2, CDNC_ECOM1P0DTF7, CDND_PSEAI
P0DSP2, CDNE_ELIMEQ89Y83, CDNG_BRADUP0DXC0, CGLR3_STYPI
A0A0H3GM48, DACA_LISM4Q8Y5E4, DACA_LISMOP47351, DACB_MYCGE
P75528, DACB_MYCPND4GZM5, DACZ_HALVDQ58408, DACZ_METJA
A3DGC7, DISA_ACET2A0LRE3, DISA_ACIC1C3P9M9, DISA_BACAA
C3LJ56, DISA_BACACA0R8F5, DISA_BACAHQ81VV7, DISA_BACAN
B7JK90, DISA_BACC0Q73FC3, DISA_BACC1B7ISZ3, DISA_BACC2
C1ET13, DISA_BACC3B7HJ22, DISA_BACC4B7HQR7, DISA_BACC7
B9IZG8, DISA_BACCQQ81J64, DISA_BACCRQ63HB6, DISA_BACCZ
Q6HPT4, DISA_BACHKQ65PD4, DISA_BACLDA9VN96, DISA_BACMK
A8F956, DISA_BACP2P37573, DISA_BACSUC5C1B3, DISA_BEUC1
Q3A9N3, DISA_CARHZQ97EC6, DISA_CLOABA7FZ95, DISA_CLOB1
C3KVS9, DISA_CLOB6A6LPN7, DISA_CLOB8B2UY85, DISA_CLOBA
B2TIF1, DISA_CLOBBA5I7N4, DISA_CLOBHC1FNB1, DISA_CLOBJ
B1IGI2, DISA_CLOBKA7GJA2, DISA_CLOBLB1KTB1, DISA_CLOBM
Q18CB2, DISA_CLOD6A5N4M2, DISA_CLOK5Q8XHQ0, DISA_CLOPE
Q0SQB6, DISA_CLOPSQ890L8, DISA_CLOTEQ8FMH9, DISA_COREF
A4QH66, DISA_CORGBQ8NMB2, DISA_CORGLQ6AAZ9, DISA_CUTAK
Q0RBN2, DISA_FRAAAQ2J537, DISA_FRACCQ8RGW9, DISA_FUSNN
Q9KGG0, DISA_HALH5A6W5K2, DISA_KINRDA0QAA9, DISA_MYCA1
Q7TW52, DISA_MYCBOA1KPS2, DISA_MYCBPC1AI45, DISA_MYCBT
Q743W9, DISA_MYCPAA0R564, DISA_MYCS2A5U8R1, DISA_MYCTA
P9WNW4, DISA_MYCTOP9WNW5, DISA_MYCTUA8LF79, DISA_PARS2
Q5WLT9, DISA_SHOC1Q82EA6, DISA_STRAWQ9X8L6, DISA_STRCO
B1VSK3, DISA_STRGGQ67JP1, DISA_SYMTHQ9WY43, DISA_THEMA
B9K6S9, DISA_THENNA5IKM1, DISA_THEP1

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.7.7.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.7.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-