ENZYME entry: EC 2.7.7.86
| Accepted Name | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| cyclic GMP-AMP synthase | |||||||||||||||||||
| Reaction catalysed | |||||||||||||||||||
| GTP + ATP = 2',3'-cGAMP + 2 diphosphate | |||||||||||||||||||
| Comment(s) | |||||||||||||||||||
| Cyclic Gp(2'-5')Ap(3'-5') is a signaling molecule in mammalian cells that triggers the production of type I interferons and other cytokines. | |||||||||||||||||||
| Cross-references | |||||||||||||||||||
| BRENDA | 2.7.7.86 | ||||||||||||||||||
| EC2PDB | 2.7.7.86 | ||||||||||||||||||
| ExplorEnz | 2.7.7.86 | ||||||||||||||||||
| KEGG Ligand Database for Enzyme Nomenclature | 2.7.7.86 | ||||||||||||||||||
| IUBMB Enzyme Nomenclature | 2.7.7.86 | ||||||||||||||||||
| MEDLINE | Find literature relating to 2.7.7.86 | ||||||||||||||||||
| MetaCyc | 2.7.7.86 | ||||||||||||||||||
| Rhea expert-curated reactions | 2.7.7.86 | ||||||||||||||||||
| UniProtKB/Swiss-Prot |
| ||||||||||||||||||
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