ENZYME entry: EC 2.7.8.33
| Accepted Name |
|---|
| UDP-N-acetylglucosamine--undecaprenyl-phosphate
N-acetylglucosaminephosphotransferase.
|
| Alternative Name(s) |
|---|
| UDP-GlcNAc:undecaprenyl-phosphate GlcNAc-1-phosphate transferase. |
| Undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate
transferase. |
| Reaction catalysed |
|---|
| UDP-N-acetyl-alpha-D-glucosamine + ditrans,octacis-undecaprenyl phosphate <=> UMP + N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol |
| Comment(s) |
|---|
- This enzyme catalyzes the synthesis of N-acetyl-alpha-D-glucosaminyl-
diphospho-ditrans,octacis-undecaprenol, an essential lipid
intermediate for the biosynthesis of various bacterial cell envelope
components.
- The enzyme also initiates the biosynthesis of enterobacterial common
antigen and O-antigen lipopolysaccharide in certain Escherichia coli
strains, including K-12 and of teichoic acid in certain Gram-positive
bacteria.
- Formerly EC 2.7.8.n2.
|
| Cross-references |
|---|
| BRENDA | 2.7.8.33 |
| EC2PDB | 2.7.8.33 |
| ExplorEnz | 2.7.8.33 |
| PRIAM enzyme-specific profiles | 2.7.8.33 |
| KEGG Ligand Database for Enzyme Nomenclature | 2.7.8.33 |
| IUBMB Enzyme Nomenclature | 2.7.8.33 |
| IntEnz | 2.7.8.33 |
| MEDLINE | Find literature relating to 2.7.8.33 |
| MetaCyc | 2.7.8.33 |
| UniProtKB/Swiss-Prot |
| O34753, TAGO_BACSU; | Q8XAS7, WECA_ECO57; | P0AC79, WECA_ECOL6; |
| P0AC78, WECA_ECOLI; | P45341, WECA_HAEIN; | Q9CNG8, WECA_PASMU; |
| Q8Z386, WECA_SALTI; | Q9L6R7, WECA_SALTY; | P0AC80, WECA_SHIFL; |
| Q9X1N5, WECA_THEMA; | Q8ZAE1, WECA_YERPE; |
|
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