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ENZYME

ENZYME entry: EC 2.7.8.5

PURL: https://purl.expasy.org/enzyme/EC/2.7.8.5
Accepted Name
CDP-diacylglycerol--glycerol-3-phosphate 1-phosphatidyltransferase
Alternative Name(s)
3-phosphatidyl-1'-glycerol-3'-phosphate synthase
glycerophosphate phosphatidyltransferase
PGP synthase
phosphatidylglycerophosphate synthase
Reaction catalysed
a CDP-1,2-diacyl-sn-glycerol + sn-glycerol 3-phosphate = a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycero-3'-phosphate) + CMP + H(+)
Comment(s)
The enzyme catalyzes the committed step in the biosynthesis of acidic phospholipids known by the common names phophatidylglycerols and cardiolipins.
Cross-references
BRENDA2.7.8.5
EC2PDB2.7.8.5
ExplorEnz2.7.8.5
KEGG Ligand Database for Enzyme Nomenclature2.7.8.5
IUBMB Enzyme Nomenclature2.7.8.5
MEDLINEFind literature relating to 2.7.8.5
MetaCyc2.7.8.5
Rhea expert-curated reactions2.7.8.5
UniProtKB/Swiss-Prot
O80952, PGPS1_ARATHQ2KJ28, PGPS1_BOVINQ5ZHN9, PGPS1_CHICK
Q9Z2Z7, PGPS1_CRIGRQ7KWX2, PGPS1_DICDIQ32NB8, PGPS1_HUMAN
Q8BHF7, PGPS1_MOUSEQ5N9A1, PGPS1_ORYSJQ5R8K7, PGPS1_PONAB
P79001, PGPS1_SACPSQ9HDW1, PGPS1_SCHPOP25578, PGPS1_YEAST
Q9M2W3, PGPS2_ARATHO67908, PGSA_AQUAEP46322, PGSA_BACSU
Q7VR12, PGSA_BLOFLQ492P7, PGSA_BLOPBQ3IYX7, PGSA_CERS4
P0ABG0, PGSA_ECO57A1AC64, PGSA_ECOK1Q0TGS6, PGSA_ECOL5
P0ABF9, PGSA_ECOL6P0ABF8, PGSA_ECOLIQ1RAM8, PGSA_ECOUT
P44528, PGSA_HAEINP47360, PGSA_MYCGEP75520, PGSA_MYCPN
P9WPG2, PGSA_MYCTOP9WPG3, PGSA_MYCTUQ6D364, PGSA_PECAS
Q7N5C8, PGSA_PHOLLP45419, PGSA_PSEFLQ1RKM3, PGSA_RICBR
Q92JJ2, PGSA_RICCNQ4UN77, PGSA_RICFEQ9ZE96, PGSA_RICPR
Q68XS5, PGSA_RICTYQ57N57, PGSA_SALCHQ5PI18, PGSA_SALPA
Q8XFD0, PGSA_SALTIQ7CQB9, PGSA_SALTYQ322L9, PGSA_SHIBS
Q32HD9, PGSA_SHIDSQ0T3L5, PGSA_SHIF8Q83R47, PGSA_SHIFL
Q3Z2T6, PGSA_SHISSQ2NTS8, PGSA_SODGMQ5HGE8, PGSA_STAAC
P63755, PGSA_STAAMP63756, PGSA_STAANQ6GHF2, PGSA_STAAR
Q6G9T0, PGSA_STAASP63757, PGSA_STAAWQ5HPQ8, PGSA_STAEQ
Q8CPF7, PGSA_STAESO66076, PGSA_TREPAQ8D2N9, PGSA_WIGBR
A1JLU9, PGSA_YERE8Q1C8L0, PGSA_YERPAQ8ZF51, PGSA_YERPE
Q1CHE5, PGSA_YERPNA4TK40, PGSA_YERPPQ66BN4, PGSA_YERPS

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.7.8.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.7.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-