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ENZYME

ENZYME entry: EC 2.8.1.10

PURL: https://purl.expasy.org/enzyme/EC/2.8.1.10
Accepted Name
thiazole synthase
Reaction catalysed
[ThiS sulfur-carrier protein]-C-terminal-Gly-aminoethanethioate + 2-iminoacetate + 1-deoxy-D-xylulose 5-phosphate = [ThiS sulfur-carrier protein]-C-terminal Gly-Gly + 2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate + 2 H2O + H(+)
Comment(s)
  • H2S can provide the sulfur in vitro.
  • Part of the pathway for thiamine biosynthesis.
Cross-references
Rhea expert-curated reactions2.8.1.10
ExplorEnz2.8.1.10
IUBMB Enzyme Nomenclature2.8.1.10
UniProtKB/Swiss-Prot
Q3A7P5, THIG1_SYNC1Q3A6Y9, THIG2_SYNC1B0C390, THIG_ACAM1
A3DD04, THIG_ACET2Q6FCN1, THIG_ACIADB7GZV4, THIG_ACIB3
B7I2M9, THIG_ACIB5B2HUU9, THIG_ACIBCB0VKA4, THIG_ACIBS
A3M6Z4, THIG_ACIBTB0V876, THIG_ACIBYB7J5U0, THIG_ACIF2
B5ENK9, THIG_ACIF5A4SSI2, THIG_AERS4Q8UCD2, THIG_AGRFC
A8ER78, THIG_ALIB4Q5E8W6, THIG_ALIF1B5FF70, THIG_ALIFM
B6EGV5, THIG_ALISLQ0ACP4, THIG_ALKEHA6TVU7, THIG_ALKMQ
B4S2W0, THIG_ALTMDB8JH75, THIG_ANAD2Q2IKW1, THIG_ANADE
A7HA08, THIG_ANADFB4UIG2, THIG_ANASKB7GEY2, THIG_ANOFW
O67926, THIG_AQUAEQ5P5J1, THIG_AROAEA8IEY6, THIG_AZOC5
A1KCM9, THIG_AZOSBC1DI61, THIG_AZOVDC3P0L4, THIG_BACAA
C3LFA6, THIG_BACACA0RA08, THIG_BACAHQ81UX4, THIG_BACAN
B7JRB1, THIG_BACC0Q73DB1, THIG_BACC1B7IY02, THIG_BACC2
C1EYJ3, THIG_BACC3B7HDF2, THIG_BACC4B7HWF4, THIG_BACC7
A7GLF8, THIG_BACCNB9J523, THIG_BACCQQ81HQ5, THIG_BACCR
Q63FR5, THIG_BACCZQ5LCA6, THIG_BACFNQ64TA0, THIG_BACFR
Q6HN84, THIG_BACHKQ65L94, THIG_BACLDA9VFL4, THIG_BACMK
A8FC15, THIG_BACP2O31618, THIG_BACSUQ8AA14, THIG_BACTN
A7Z3F8, THIG_BACVZA1US08, THIG_BARBKQ6G480, THIG_BARHE
Q6G0A2, THIG_BARQUA9IRH0, THIG_BART1Q1LU41, THIG_BAUCH
Q8G5F6, THIG_BIFLOQ2KUI1, THIG_BORA1Q7WF21, THIG_BORBR
Q7W3P5, THIG_BORPAQ7VTE5, THIG_BORPEQ89FP2, THIG_BRADU
A5EPQ3, THIG_BRASBA4YZQ4, THIG_BRASOB2S8J9, THIG_BRUA1
Q2YP58, THIG_BRUA2A6WVK9, THIG_BRUA4Q57FG5, THIG_BRUAB
A9M7F3, THIG_BRUC2C0RGR3, THIG_BRUMBQ8YEZ2, THIG_BRUME
A5VNE4, THIG_BRUO2B0CJ70, THIG_BRUSIQ8G2U9, THIG_BRUSU
Q39KA4, THIG_BURL3Q62GC6, THIG_BURMAQ3JMY2, THIG_BURP1
Q63Q73, THIG_BURPSQ2SU89, THIG_BURTAA8FM94, THIG_CAMJ8
A7H2Z6, THIG_CAMJDQ9PNP6, THIG_CAMJEA1W035, THIG_CAMJJ
Q5HU56, THIG_CAMJRB0SXB0, THIG_CAUSKQ9A746, THIG_CAUVC
B8GWN0, THIG_CAUVNB3PIG8, THIG_CELJUQ3AR47, THIG_CHLCH
B3EH68, THIG_CHLL2B3QMD7, THIG_CHLP8B3EK52, THIG_CHLPB
A1BEF7, THIG_CHLPDA4SFW2, THIG_CHLPMB3QUZ7, THIG_CHLT3
Q8KEJ1, THIG_CHLTEQ7NRL4, THIG_CHRVOB5ED95, THIG_CITBB
A8AKT3, THIG_CITK8P58262, THIG_CLOABA6LTL5, THIG_CLOB8
Q186R1, THIG_CLOD6A5N8P8, THIG_CLOK5Q0TQ02, THIG_CLOP1
Q8XK02, THIG_CLOPEQ0SSM0, THIG_CLOPSQ893R2, THIG_CLOTE
Q48A93, THIG_COLP3C3PH66, THIG_CORA7Q6NKI6, THIG_CORDI
Q8FP52, THIG_COREFA4QFA8, THIG_CORGBQ8NNY6, THIG_CORGL
Q4JVZ5, THIG_CORJKB1VH27, THIG_CORU7B6J5W6, THIG_COXB1
B6J1X5, THIG_COXB2A9KGN4, THIG_COXBNA9NB65, THIG_COXBR
Q83EI7, THIG_COXBUA7MQQ2, THIG_CROS8Q1LS25, THIG_CUPMC
Q0KF31, THIG_CUPNHQ476U3, THIG_CUPPJB2AGF6, THIG_CUPTR
Q6AAE4, THIG_CUTAKO19915, THIG_CYACAQ85G31, THIG_CYAM1
Q11YI1, THIG_CYTH3Q478Z2, THIG_DECARQ1IX18, THIG_DEIGD
Q9RYY1, THIG_DEIRAQ6AMF7, THIG_DESPSA4J0M0, THIG_DESRM
A7ZUK5, THIG_ECO24B7UPE5, THIG_ECO27B7MIX6, THIG_ECO45
B7LA84, THIG_ECO55P58263, THIG_ECO57B7NRS3, THIG_ECO7I
B7N2J2, THIG_ECO81B7M738, THIG_ECO8AC5A0T1, THIG_ECOBW
B1XBZ3, THIG_ECODHA8A790, THIG_ECOHSQ0TA75, THIG_ECOL5
Q8FB81, THIG_ECOL6B1IUQ7, THIG_ECOLCP30139, THIG_ECOLI
B7NFT1, THIG_ECOLUB6I5K1, THIG_ECOSEA4XZZ8, THIG_ECTM1
Q2GDS9, THIG_EHRS3Q4G387, THIG_EMIHUA4W5B3, THIG_ENT38
Q9F812, THIG_ERWAMQ8GEI4, THIG_ERWPEB2VD79, THIG_ERWT9
B7LUL2, THIG_ESCF3B1YES2, THIG_EXIA2A6GWS0, THIG_FLAPJ
Q2J8F9, THIG_FRACCQ8RI63, THIG_FUSNNQ5L2C0, THIG_GEOKA
Q39RH2, THIG_GEOMGQ74FL9, THIG_GEOSLC6E0C4, THIG_GEOSM
C5D6J1, THIG_GEOSWA4IKR6, THIG_GEOTNA5G7P4, THIG_GEOUR
B9K256, THIG_GILA4Q7NJM5, THIG_GLOVIA9HI56, THIG_GLUDA
Q5FNT5, THIG_GLUOXQ6B924, THIG_GRATLQ2SQL5, THIG_HAHCH
Q9KCY6, THIG_HALH5Q7VF28, THIG_HELHPB0TG92, THIG_HELMI
Q31JD2, THIG_HYDCUQ5R146, THIG_IDILOA6TGP7, THIG_KLEP7
B5XYE8, THIG_KLEV3Q5X4Z5, THIG_LEGPAA5IC64, THIG_LEGPC
Q5WWJ5, THIG_LEGPLB9E9B4, THIG_MACCJA0L5E8, THIG_MAGMM
Q0AQ76, THIG_MARMMA6VXY2, THIG_MARMSQ609Z5, THIG_METCA
Q1GXY7, THIG_METFKB8IPG1, THIG_METNOB0UHP4, THIG_METS4
Q2RHX4, THIG_MOOTAA0QLT3, THIG_MYCA1P59948, THIG_MYCBO
A1KFN9, THIG_MYCBPC1AK93, THIG_MYCBTB8ZU92, THIG_MYCLB
Q9ZBL2, THIG_MYCLEB2HQ02, THIG_MYCMMQ73T20, THIG_MYCPA
A0QQL0, THIG_MYCS2A5TZE3, THIG_MYCTAP9WG72, THIG_MYCTO
P9WG73, THIG_MYCTUA0PRX9, THIG_MYCUAQ1D7A6, THIG_MYXXD
B9L7B6, THIG_NAUPAQ5F5C4, THIG_NEIG1A9M072, THIG_NEIM0
Q9JWI4, THIG_NEIMAQ9JXF5, THIG_NEIMBA1KWF0, THIG_NEIMF
Q0AJ67, THIG_NITECQ82XI7, THIG_NITEUQ1QJD6, THIG_NITHX
Q2YCZ2, THIG_NITMUQ3JAP1, THIG_NITOCA6Q1C9, THIG_NITSB
Q3SPS2, THIG_NITWNQ5YNQ2, THIG_NOCFAQ2G348, THIG_NOVAD
Q311P4, THIG_OLEA2A1TRP8, THIG_PARC0A1AY12, THIG_PARDP
Q2W3R9, THIG_PARM1Q7UA46, THIG_PARMWA8LFH1, THIG_PARS2
Q6DAM4, THIG_PECASC6DHS2, THIG_PECCPB4SCL0, THIG_PELPB
A5D4K1, THIG_PELTSQ4FMP0, THIG_PELUBC0QUK5, THIG_PERMH
A0T0L1, THIG_PHATCB4RCS1, THIG_PHEZHQ7N966, THIG_PHOLL
Q6LVX7, THIG_PHOPRA6L646, THIG_PHOV8B2RH32, THIG_PORG3
Q7MT73, THIG_PORGIP51361, THIG_PORPUA3PFF2, THIG_PROM0
A2C5C9, THIG_PROM1A8G7G9, THIG_PROM2A2BZ50, THIG_PROM5
Q317X8, THIG_PROM9Q7V9K9, THIG_PROMAB4EYU5, THIG_PROMH
Q7V9A2, THIG_PROMMQ7UZJ9, THIG_PROMPA2BTP5, THIG_PROMS
Q46IC6, THIG_PROMTQ48CL9, THIG_PSE14B7V3W7, THIG_PSEA8
Q02U32, THIG_PSEABQ9I6B4, THIG_PSEAEQ1IGD3, THIG_PSEE4
Q4K4C5, THIG_PSEF5C3K3L7, THIG_PSEFSA5WAD7, THIG_PSEP1
A6UYJ0, THIG_PSEP7Q3K587, THIG_PSEPFB0KN58, THIG_PSEPG
Q88CS6, THIG_PSEPKB1J2G8, THIG_PSEPWQ88AF6, THIG_PSESM
Q3IFN6, THIG_PSET1Q4ZM55, THIG_PSEU2Q4FV61, THIG_PSYA2
Q1QE71, THIG_PSYCKQ1XDC6, THIG_PYRYEQ8Y372, THIG_RALN1
B2U764, THIG_RALPJO34293, THIG_RHIECQ98AZ6, THIG_RHILO
P58264, THIG_RHIMEB9JMX8, THIG_RHIR8Q7US84, THIG_RHOBA
Q2IYP6, THIG_RHOP2Q07PW9, THIG_RHOP5Q6N3W7, THIG_RHOPA
Q216G8, THIG_RHOPBQ133T5, THIG_RHOPSB3QFS7, THIG_RHOPT
Q2RRL3, THIG_RHORTQ16C60, THIG_ROSDOQ5LWJ1, THIG_RUEPO
B5F1H3, THIG_SALA4A8M4E3, THIG_SALAIA9MHE0, THIG_SALAR
Q57H64, THIG_SALCHB5QYE5, THIG_SALEPB5RFJ4, THIG_SALG2
Q5PK87, THIG_SALPAA9N0K2, THIG_SALPBC0Q2S2, THIG_SALPC
B5BJQ9, THIG_SALPKQ2S371, THIG_SALRDB4TQK0, THIG_SALSV
Q8Z322, THIG_SALTIQ9L9J1, THIG_SALTYA8G8F0, THIG_SERP5
A1S6Q5, THIG_SHEAMB8EA59, THIG_SHEB2A3D465, THIG_SHEB5
A6WNR8, THIG_SHEB8A9L3J3, THIG_SHEB9Q12NB8, THIG_SHEDO
Q081M2, THIG_SHEFNB0TS89, THIG_SHEHHA3QER0, THIG_SHELP
Q8EEE1, THIG_SHEONA8H562, THIG_SHEPAA4Y6R6, THIG_SHEPC
B8CNW1, THIG_SHEPWA0KWK2, THIG_SHESAA8FUV3, THIG_SHESH
Q0HJ08, THIG_SHESMQ0HUX4, THIG_SHESRA1RJR5, THIG_SHESW
B1KHI0, THIG_SHEWMB2TWH8, THIG_SHIB3Q31U06, THIG_SHIBS
Q32AG3, THIG_SHIDSQ83PC0, THIG_SHIFLQ3YUZ4, THIG_SHISS
Q5WH85, THIG_SHOC1Q01NZ1, THIG_SOLUEA9EXF3, THIG_SORC5
B9DKG1, THIG_STACTQ5HLB4, THIG_STAEQQ8CN30, THIG_STAES
Q4L904, THIG_STAHJQ49UF2, THIG_STAS1Q82AG5, THIG_STRAW
Q9S2N4, THIG_STRCOB1VZU6, THIG_STRGGB4STS6, THIG_STRM5
B2FSD0, THIG_STRMKA4VRK5, THIG_STUS1Q30U33, THIG_SULDN
B2V959, THIG_SULSYQ31QR1, THIG_SYNE7A0LJA4, THIG_SYNFM
Q5N3I3, THIG_SYNP6A5GHR6, THIG_SYNPWQ3B0V2, THIG_SYNS9
Q3ANJ9, THIG_SYNSCA0T103, THIG_THAPSQ47R37, THIG_THEFY
Q72KN9, THIG_THET2Q5SKG7, THIG_THET8Q8DMP6, THIG_THEVB
B5YJ73, THIG_THEYDQ3SH10, THIG_THIDAB8GQT0, THIG_THISH
P49570, THIG_TRICVQ112X4, THIG_TRIEIC5CJH0, THIG_VARPS
A5CVZ0, THIG_VESOHB7VMV3, THIG_VIBA3A7N137, THIG_VIBC1
A5F4E2, THIG_VIBC3Q9KVS4, THIG_VIBCHC3LPQ7, THIG_VIBCM
Q87KF4, THIG_VIBPAQ8DDL8, THIG_VIBVUQ7MGM7, THIG_VIBVY
Q8D249, THIG_WIGBRQ7M9F6, THIG_WOLSUQ8PHF5, THIG_XANC3
Q4UXY4, THIG_XANC8B0RPJ1, THIG_XANCBQ8P632, THIG_XANCP
Q3BQ15, THIG_XANE5Q2P0J5, THIG_XANOMB2SWK7, THIG_XANOP
Q5GXE5, THIG_XANORQ9PF95, THIG_XYLFAQ87AE8, THIG_XYLFT
A1JII4, THIG_YERE8A7FNH9, THIG_YERP3Q1C1U5, THIG_YERPA
B2K116, THIG_YERPBQ8ZAP9, THIG_YERPEQ1CN74, THIG_YERPN
Q66FP9, THIG_YERPSB1JJK2, THIG_YERPYQ5NPJ8, THIG_ZYMMO
Q8YRC9, THIOG_NOSS1Q55710, THIOG_SYNY3Q3M859, THIOG_TRIV2
BRENDA2.8.1.10
MetaCyc2.8.1.10
KEGG Ligand Database for Enzyme Nomenclature2.8.1.10
MEDLINEFind literature relating to 2.8.1.10

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.8.1.-
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