ID   2.8.1.6
DE   Biotin synthase.
CA   Dethiobiotin + sulfur-(sulfur carrier) + 2 S-adenosyl-L-methionine +
CA   2 reduced [2Fe-2S] ferredoxin = biotin + (sulfur carrier) +
CA   2 L-methionine + 2 5'-deoxyadenosine + 2 oxidized [2Fe-2S] ferredoxin.
CF   Iron-sulfur.
CC   -!- The enzyme binds a [4Fe-4S] and a [2Fe-2S] cluster.
CC   -!- In every reaction cycle, the enzyme consumes two molecules of AdoMet,
CC       each producing 5'-deoxyadenosine and 4,5-secobiotin.
CC   -!- Reaction with another equivalent of AdoMet results in abstraction of
CC       the C6 methylene pro-S hydrogen atom from 4,5-secobiotin, and the
CC       resulting carbon radical is quenched via formation of an
CC       intramolecular C-S bond, thus closing the biotin thiophane ring.
CC   -!- The sulfur donor is believed to be the [2Fe-2S] cluster, which is
CC       sacrificed in the process, so that in vitro the reaction is a single
CC       turnover.
CC   -!- In vivo, the [2Fe-2S] cluster can be reassembled by the Isc or Suf
CC       iron-sulfur cluster assembly systems, to allow further catalysis.
DR   E1WTS4, BIOAB_BACF6;  Q5LEY1, BIOAB_BACFN;  Q64VX4, BIOAB_BACFR;
DR   E6SRG2, BIOAB_BACT6;  Q8A7T2, BIOAB_BACTN;  Q6NKC7, BIOB1_CORDI;
DR   Q2J6H8, BIOB1_FRACC;  A1B1Z0, BIOB1_PARDP;  Q12F39, BIOB1_POLSJ;
DR   Q6NHL3, BIOB2_CORDI;  Q2J5A7, BIOB2_FRACC;  A1B656, BIOB2_PARDP;
DR   Q12D73, BIOB2_POLSJ;  B0CC69, BIOB_ACAM1 ;  A3DBD3, BIOB_ACET2 ;
DR   A1TQ53, BIOB_ACIAC ;  Q6FAP9, BIOB_ACIAD ;  B7H3S4, BIOB_ACIB3 ;
DR   B7I4I4, BIOB_ACIB5 ;  B2HYX9, BIOB_ACIBC ;  B0VR41, BIOB_ACIBS ;
DR   A3M4U4, BIOB_ACIBT ;  B0VCA8, BIOB_ACIBY ;  A0LTP8, BIOB_ACIC1 ;
DR   Q93GG2, BIOB_ACICA ;  A5FZN9, BIOB_ACICJ ;  B9MJH4, BIOB_ACIET ;
DR   B7J403, BIOB_ACIF2 ;  B5ELR8, BIOB_ACIF5 ;  A1W7J6, BIOB_ACISJ ;
DR   A3MYI9, BIOB_ACTP2 ;  B3GZV8, BIOB_ACTP7 ;  B0BS22, BIOB_ACTPJ ;
DR   A6VNF1, BIOB_ACTSZ ;  A0KIC6, BIOB_AERHH ;  A4SPR7, BIOB_AERS4 ;
DR   B6JDD7, BIOB_AFIC5 ;  A9CFX5, BIOB_AGRFC ;  B9J9I5, BIOB_AGRRK ;
DR   B9JYY6, BIOB_AGRVS ;  B2UNW0, BIOB_AKKM8 ;  Q0VMD0, BIOB_ALCBS ;
DR   A8EWX7, BIOB_ALIB4 ;  B1WN69, BIOB_ALIF1 ;  B5EUQ0, BIOB_ALIFM ;
DR   B6ESC7, BIOB_ALISL ;  Q0A5W1, BIOB_ALKEH ;  Q9KC26, BIOB_ALKHC ;
DR   A6TT61, BIOB_ALKMQ ;  B4S0P9, BIOB_ALTMD ;  B8J638, BIOB_ANAD2 ;
DR   Q2IF61, BIOB_ANADE ;  A7HG97, BIOB_ANADF ;  B9KGM2, BIOB_ANAMF ;
DR   Q5PA14, BIOB_ANAMM ;  Q2GLB4, BIOB_ANAPZ ;  B4UCB2, BIOB_ANASK ;
DR   B7GKT8, BIOB_ANOFW ;  O67104, BIOB_AQUAE ;  P54967, BIOB_ARATH ;
DR   Q5P7M6, BIOB_AROAE ;  A0JTA3, BIOB_ARTS2 ;  A8IJU8, BIOB_AZOC5 ;
DR   A1K9C8, BIOB_AZOSB ;  A0RIB6, BIOB_BACAH ;  Q70JZ1, BIOB_BACAM ;
DR   Q81MB3, BIOB_BACAN ;  B7JLW9, BIOB_BACC0 ;  Q731I2, BIOB_BACC1 ;
DR   B7IWM8, BIOB_BACC2 ;  B7HAY7, BIOB_BACC4 ;  B7HNN1, BIOB_BACC7 ;
DR   A7GSD8, BIOB_BACCN ;  B9IWX7, BIOB_BACCQ ;  Q818X3, BIOB_BACCR ;
DR   Q635G7, BIOB_BACCZ ;  Q6HE51, BIOB_BACHK ;  Q65MK9, BIOB_BACLD ;
DR   A9VG53, BIOB_BACMK ;  Q8KZM7, BIOB_BACNA ;  A8FGR8, BIOB_BACP2 ;
DR   P53557, BIOB_BACSU ;  A7Z5B2, BIOB_BACVZ ;  Q1LTL8, BIOB_BAUCH ;
DR   B2IEZ6, BIOB_BEII9 ;  Q2KWF1, BIOB_BORA1 ;  Q7WMQ3, BIOB_BORBR ;
DR   Q7WB85, BIOB_BORPA ;  A9I023, BIOB_BORPD ;  Q7VVF1, BIOB_BORPE ;
DR   Q9AMS7, BIOB_BRADU ;  C0QVM0, BIOB_BRAHW ;  A5EFG5, BIOB_BRASB ;
DR   A4YQS3, BIOB_BRASO ;  B2SBF0, BIOB_BRUA1 ;  Q2YKB8, BIOB_BRUA2 ;
DR   A6X2S8, BIOB_BRUA4 ;  Q577P8, BIOB_BRUAB ;  A9MBD6, BIOB_BRUC2 ;
DR   C0RL26, BIOB_BRUMB ;  Q8YBW1, BIOB_BRUME ;  A5VUG1, BIOB_BRUO2 ;
DR   A9WYH2, BIOB_BRUSI ;  Q8FWG3, BIOB_BRUSU ;  B8D983, BIOB_BUCA5 ;
DR   P57378, BIOB_BUCAI ;  Q8K9P1, BIOB_BUCAP ;  B8D7I5, BIOB_BUCAT ;
DR   Q89AK5, BIOB_BUCBP ;  B1YNS2, BIOB_BURA4 ;  Q1BT34, BIOB_BURCA ;
DR   B1JZE1, BIOB_BURCC ;  A0KB05, BIOB_BURCH ;  B4E9L4, BIOB_BURCJ ;
DR   Q0BBD4, BIOB_BURCM ;  Q39CE4, BIOB_BURL3 ;  A9AE44, BIOB_BURM1 ;
DR   A3MNG1, BIOB_BURM7 ;  A2S7R3, BIOB_BURM9 ;  Q62MW9, BIOB_BURMA ;
DR   A1V817, BIOB_BURMS ;  A3NQS1, BIOB_BURP0 ;  Q3JWR8, BIOB_BURP1 ;
DR   A3N520, BIOB_BURP6 ;  Q63Y25, BIOB_BURPS ;  Q2T1Q4, BIOB_BURTA ;
DR   A4JIB7, BIOB_BURVG ;  B9MP50, BIOB_CALBD ;  A4XGB8, BIOB_CALS8 ;
DR   A7ZFR4, BIOB_CAMC1 ;  A7H0I4, BIOB_CAMC5 ;  A0RME8, BIOB_CAMFF ;
DR   A7I1A0, BIOB_CAMHC ;  A8FNZ2, BIOB_CAMJ8 ;  A7H632, BIOB_CAMJD ;
DR   Q0P7U6, BIOB_CAMJE ;  A1W1T3, BIOB_CAMJJ ;  Q5HSB2, BIOB_CAMJR ;
DR   B9KEN8, BIOB_CAMLR ;  Q3ADP5, BIOB_CARHZ ;  B0T1Y4, BIOB_CAUSK ;
DR   Q9A2N5, BIOB_CAUVC ;  B8H640, BIOB_CAUVN ;  B3PI87, BIOB_CELJU ;
DR   A0RW96, BIOB_CENSY ;  A3PH74, BIOB_CERS1 ;  Q3J561, BIOB_CERS4 ;
DR   B9KM96, BIOB_CERSK ;  Q5L5F9, BIOB_CHLAB ;  Q3ANX4, BIOB_CHLCH ;
DR   Q255G8, BIOB_CHLFF ;  B3EI42, BIOB_CHLL2 ;  Q3B169, BIOB_CHLL3 ;
DR   B3QLR7, BIOB_CHLP8 ;  B3EPW2, BIOB_CHLPB ;  A1BCQ5, BIOB_CHLPD ;
DR   A4SGW2, BIOB_CHLPM ;  Q9Z6L5, BIOB_CHLPN ;  Q8KGB6, BIOB_CHLTE ;
DR   Q1QYD5, BIOB_CHRSD ;  Q7NPW1, BIOB_CHRVO ;  B5ECN1, BIOB_CITBB ;
DR   P12997, BIOB_CITFR ;  A8AJ12, BIOB_CITK8 ;  Q97MI6, BIOB_CLOAB ;
DR   A7FVS6, BIOB_CLOB1 ;  A6LUQ4, BIOB_CLOB8 ;  B2V167, BIOB_CLOBA ;
DR   B2TL73, BIOB_CLOBB ;  A5I427, BIOB_CLOBH ;  B1IHH9, BIOB_CLOBK ;
DR   A7GFJ9, BIOB_CLOBL ;  B1KW08, BIOB_CLOBM ;  Q18D35, BIOB_CLOD6 ;
DR   B9E2A2, BIOB_CLOK1 ;  A0PYU9, BIOB_CLONN ;  Q0TQ59, BIOB_CLOP1 ;
DR   Q8XK59, BIOB_CLOPE ;  Q899M1, BIOB_CLOTE ;  Q481G0, BIOB_COLP3 ;
DR   Q8FUD1, BIOB_COREF ;  A4QA10, BIOB_CORGB ;  P46396, BIOB_CORGL ;
DR   Q4JWG3, BIOB_CORJK ;  B1VF77, BIOB_CORU7 ;  B6J725, BIOB_COXB1 ;
DR   B6J074, BIOB_COXB2 ;  A9KG71, BIOB_COXBN ;  A9NCS0, BIOB_COXBR ;
DR   Q83CU5, BIOB_COXBU ;  B1WTI3, BIOB_CROS5 ;  A7MJ03, BIOB_CROS8 ;
DR   Q1LS73, BIOB_CUPMC ;  Q0KF86, BIOB_CUPNH ;  Q477A1, BIOB_CUPPJ ;
DR   B2AGA0, BIOB_CUPTR ;  Q6A7V7, BIOB_CUTAK ;  B8HPP0, BIOB_CYAP4 ;
DR   Q11S94, BIOB_CYTH3 ;  Q47IF6, BIOB_DECAR ;  A9C2R2, BIOB_DELAS ;
DR   B8FHQ1, BIOB_DESAL ;  B1I4G4, BIOB_DESAP ;  B8J0C6, BIOB_DESDA ;
DR   A8ZUS9, BIOB_DESOH ;  Q6AK48, BIOB_DESPS ;  A4J1M3, BIOB_DESRM ;
DR   Q728P5, BIOB_DESVH ;  B8DPP9, BIOB_DESVM ;  A1VB97, BIOB_DESVV ;
DR   A7ZJI4, BIOB_ECO24 ;  B7ULX2, BIOB_ECO27 ;  B7MGN3, BIOB_ECO45 ;
DR   B7LC57, BIOB_ECO55 ;  Q8X825, BIOB_ECO57 ;  B5YRL4, BIOB_ECO5E ;
DR   B7NNK5, BIOB_ECO7I ;  B7MQM8, BIOB_ECO81 ;  B7M747, BIOB_ECO8A ;
DR   B1X7A5, BIOB_ECODH ;  A7ZY31, BIOB_ECOHS ;  A1A917, BIOB_ECOK1 ;
DR   Q0TJS3, BIOB_ECOL5 ;  Q8FJQ3, BIOB_ECOL6 ;  B1IXJ3, BIOB_ECOLC ;
DR   P12996, BIOB_ECOLI ;  B7NA74, BIOB_ECOLU ;  B6I7S9, BIOB_ECOSE ;
DR   B1LM66, BIOB_ECOSM ;  Q1REF5, BIOB_ECOUT ;  Q3YRG6, BIOB_EHRCJ ;
DR   Q2GHB1, BIOB_EHRCR ;  Q5FFY2, BIOB_EHRRG ;  Q5HAN0, BIOB_EHRRW ;
DR   Q5AYI7, BIOB_EMENI ;  B1GYW9, BIOB_ENDTX ;  A4W8B7, BIOB_ENT38 ;
DR   B2VBT9, BIOB_ERWT9 ;  Q2NB65, BIOB_ERYLH ;  B7LJY8, BIOB_ESCF3 ;
DR   A5FLT1, BIOB_FLAJ1 ;  A6GW77, BIOB_FLAPJ ;  Q0RD46, BIOB_FRAAA ;
DR   B0U0S3, BIOB_FRAP2 ;  A8L2N0, BIOB_FRASN ;  Q14HR4, BIOB_FRAT1 ;
DR   A7NCW7, BIOB_FRATF ;  Q2A2V9, BIOB_FRATH ;  B2SGE3, BIOB_FRATM ;
DR   A0Q638, BIOB_FRATN ;  Q0BLD5, BIOB_FRATO ;  Q5NGB2, BIOB_FRATT ;
DR   A4IXP5, BIOB_FRATW ;  Q8REU0, BIOB_FUSNN ;  B9M305, BIOB_GEODF ;
DR   Q5KZN1, BIOB_GEOKA ;  Q39VB0, BIOB_GEOMG ;  Q74CT7, BIOB_GEOSL ;
DR   A4IN84, BIOB_GEOTN ;  A5G3Q7, BIOB_GEOUR ;  B8F6C9, BIOB_GLAP5 ;
DR   B7KFJ9, BIOB_GLOC7 ;  Q7NDA8, BIOB_GLOVI ;  A9HRF2, BIOB_GLUDA ;
DR   Q5FPC9, BIOB_GLUOX ;  Q0BUV5, BIOB_GRABC ;  A0M7A9, BIOB_GRAFK ;
DR   Q7VMH0, BIOB_HAEDU ;  Q4QLQ0, BIOB_HAEI8 ;  A5UD65, BIOB_HAEIE ;
DR   A5UIF3, BIOB_HAEIG ;  P44987, BIOB_HAEIN ;  Q0I355, BIOB_HAES1 ;
DR   Q2SBD4, BIOB_HAHCH ;  A1WVM7, BIOB_HALHL ;  Q17VA0, BIOB_HELAH ;
DR   Q7VFE6, BIOB_HELHP ;  B0TE53, BIOB_HELMI ;  B6JNP9, BIOB_HELP2 ;
DR   B5Z928, BIOB_HELPG ;  Q1CRM5, BIOB_HELPH ;  Q9ZJK8, BIOB_HELPJ ;
DR   B2UVE8, BIOB_HELPS ;  O25956, BIOB_HELPY ;  A4G1F1, BIOB_HERAR ;
DR   B0UUK6, BIOB_HISS2 ;  Q31E55, BIOB_HYDCU ;  B4U973, BIOB_HYDS0 ;
DR   Q0C661, BIOB_HYPNA ;  Q5QZ16, BIOB_IDILO ;  A6SU66, BIOB_JANMA ;
DR   B5XZ75, BIOB_KLEP3 ;  A6T6L5, BIOB_KLEP7 ;  B2GLQ7, BIOB_KOCRD ;
DR   Q1MRA1, BIOB_LAWIP ;  Q5X592, BIOB_LEGPA ;  A5IBW2, BIOB_LEGPC ;
DR   Q5ZVG8, BIOB_LEGPH ;  Q5WW97, BIOB_LEGPL ;  B0SDC5, BIOB_LEPBA ;
DR   Q04RS9, BIOB_LEPBJ ;  Q051U2, BIOB_LEPBL ;  B0SLQ3, BIOB_LEPBP ;
DR   B1Y502, BIOB_LEPCP ;  Q72RG8, BIOB_LEPIC ;  Q8F498, BIOB_LEPIN ;
DR   B1HRT3, BIOB_LYSSC ;  P19206, BIOB_LYSSH ;  B9EA22, BIOB_MACCJ ;
DR   A0L3M0, BIOB_MAGMM ;  Q2W3L4, BIOB_MAGSA ;  Q65SD0, BIOB_MANSM ;
DR   Q0ATN3, BIOB_MARMM ;  A6W0Y1, BIOB_MARMS ;  A1U4B2, BIOB_MARN8 ;
DR   C6C0T2, BIOB_MARSD ;  A6UTF3, BIOB_META3 ;  B7KN34, BIOB_METC4 ;
DR   Q609V2, BIOB_METCA ;  A9W8M8, BIOB_METEP ;  Q1GZA6, BIOB_METFK ;
DR   B3DV36, BIOB_METI4 ;  Q58692, BIOB_METJA ;  A4FWU0, BIOB_METM5 ;
DR   A9AA75, BIOB_METM6 ;  A6VGH7, BIOB_METM7 ;  Q6LXV8, BIOB_METMP ;
DR   B8IU36, BIOB_METNO ;  B1ZFX7, BIOB_METPB ;  A2SGQ6, BIOB_METPP ;
DR   B1LV19, BIOB_METRJ ;  B0U811, BIOB_METS4 ;  B8EMZ5, BIOB_METSB ;
DR   P94966, BIOB_METSK ;  A6UPN7, BIOB_METVS ;  B0JFP4, BIOB_MICAN ;
DR   A0QHJ1, BIOB_MYCA1 ;  B1MBZ3, BIOB_MYCA9 ;  P0A507, BIOB_MYCBO ;
DR   A1KJ05, BIOB_MYCBP ;  A4T9L9, BIOB_MYCGI ;  B8ZR86, BIOB_MYCLB ;
DR   P46715, BIOB_MYCLE ;  B2HQ93, BIOB_MYCMM ;  Q740Q9, BIOB_MYCPA ;
DR   A0QX70, BIOB_MYCS2 ;  A3Q142, BIOB_MYCSJ ;  A1UHL9, BIOB_MYCSK ;
DR   Q1B7F4, BIOB_MYCSS ;  A5U2U5, BIOB_MYCTA ;  A5WMR0, BIOB_MYCTF ;
DR   P9WPQ6, BIOB_MYCTO ;  P9WPQ7, BIOB_MYCTU ;  A0PP05, BIOB_MYCUA ;
DR   A1T8V0, BIOB_MYCVP ;  Q1DCV9, BIOB_MYXXD ;  Q3INU3, BIOB_NATPD ;
DR   B9L7E1, BIOB_NAUPA ;  Q5F8G2, BIOB_NEIG1 ;  B4RLI6, BIOB_NEIG2 ;
DR   A9LZ69, BIOB_NEIM0 ;  A1IRY3, BIOB_NEIMA ;  Q9JRW7, BIOB_NEIMB ;
DR   A1KU01, BIOB_NEIMF ;  Q2GDF4, BIOB_NEOSM ;  Q0AE72, BIOB_NITEC ;
DR   Q82SL7, BIOB_NITEU ;  Q1QRH1, BIOB_NITHX ;  A9A5K6, BIOB_NITMS ;
DR   Q2Y9Y9, BIOB_NITMU ;  Q3J9D5, BIOB_NITOC ;  A6Q5K0, BIOB_NITSB ;
DR   Q3SW30, BIOB_NITWN ;  Q5YYR3, BIOB_NOCFA ;  A1SM80, BIOB_NOCSJ ;
DR   B2J914, BIOB_NOSP7 ;  Q8YVQ3, BIOB_NOSS1 ;  Q2GAF7, BIOB_NOVAD ;
DR   Q30XZ5, BIOB_OLEA2 ;  A1R3R7, BIOB_PAEAT ;  A6LD84, BIOB_PARD8 ;
DR   A7HP26, BIOB_PARL1 ;  Q7U7P8, BIOB_PARMW ;  B2JKH4, BIOB_PARP8 ;
DR   B2SWS5, BIOB_PARPJ ;  Q146K5, BIOB_PARXL ;  Q9CNP8, BIOB_PASMU ;
DR   Q6D3B9, BIOB_PECAS ;  B4SGZ7, BIOB_PELPB ;  A1AN77, BIOB_PELPD ;
DR   A5D4Y6, BIOB_PELTS ;  C0QR28, BIOB_PERMH ;  B4RBP5, BIOB_PHEZH ;
DR   Q7N6Q7, BIOB_PHOLL ;  Q6LPR2, BIOB_PHOPR ;  A4SV63, BIOB_POLAQ ;
DR   A1VUJ4, BIOB_POLNA ;  B2RH08, BIOB_PORG3 ;  Q7MT97, BIOB_PORGI ;
DR   B4S690, BIOB_PROA2 ;  A3PDJ8, BIOB_PROM0 ;  A2C3I4, BIOB_PROM1 ;
DR   A8G5G3, BIOB_PROM2 ;  A2C8D5, BIOB_PROM3 ;  A9BB12, BIOB_PROM4 ;
DR   A2BX80, BIOB_PROM5 ;  Q31AD2, BIOB_PROM9 ;  Q7VBJ0, BIOB_PROMA ;
DR   B4ESU3, BIOB_PROMH ;  Q7V6T8, BIOB_PROMM ;  Q7V101, BIOB_PROMP ;
DR   A2BRS2, BIOB_PROMS ;  Q46K32, BIOB_PROMT ;  Q48CS1, BIOB_PSE14 ;
DR   Q15SR5, BIOB_PSEA6 ;  A6UYW0, BIOB_PSEA7 ;  B7V485, BIOB_PSEA8 ;
DR   Q02TR6, BIOB_PSEAB ;  Q9I618, BIOB_PSEAE ;  B8HDH4, BIOB_PSECP ;
DR   Q1I3N6, BIOB_PSEE4 ;  Q4K4T2, BIOB_PSEF5 ;  A4XZR9, BIOB_PSEMY ;
DR   A5VXF1, BIOB_PSEP1 ;  Q3K5P1, BIOB_PSEPF ;  B0KJ53, BIOB_PSEPG ;
DR   Q88QX2, BIOB_PSEPK ;  B1JE55, BIOB_PSEPW ;  Q88A98, BIOB_PSESM ;
DR   Q3IGS6, BIOB_PSET1 ;  Q4ZMA8, BIOB_PSEU2 ;  A4VR88, BIOB_PSEU5 ;
DR   Q47862, BIOB_PSEVU ;  Q4FQJ9, BIOB_PSYA2 ;  Q1Q8S6, BIOB_PSYCK ;
DR   A1SW31, BIOB_PSYIN ;  A5WHI6, BIOB_PSYWF ;  B2UDA1, BIOB_RALPJ ;
DR   Q8Y2R9, BIOB_RALSO ;  A9WL37, BIOB_RENSM ;  A5VAC6, BIOB_RHIWR ;
DR   Q7UF84, BIOB_RHOBA ;  Q21W43, BIOB_RHOFT ;  Q0SHW6, BIOB_RHOJR ;
DR   Q2IUT3, BIOB_RHOP2 ;  Q07PI4, BIOB_RHOP5 ;  Q6N859, BIOB_RHOPA ;
DR   Q212A8, BIOB_RHOPB ;  Q138Z3, BIOB_RHOPS ;  B3QCX3, BIOB_RHOPT ;
DR   Q4UM45, BIOB_RICFE ;  B7K1U3, BIOB_RIPO1 ;  Q5LN74, BIOB_RUEPO ;
DR   A1AWE7, BIOB_RUTMC ;  Q21FY3, BIOB_SACD2 ;  A4FIS6, BIOB_SACEN ;
DR   B5F072, BIOB_SALA4 ;  A8LUR1, BIOB_SALAI ;  A9MJE6, BIOB_SALAR ;
DR   Q57RG3, BIOB_SALCH ;  B5FP61, BIOB_SALDC ;  B5QX65, BIOB_SALEP ;
DR   B5R761, BIOB_SALG2 ;  B4TC48, BIOB_SALHS ;  B4SZJ7, BIOB_SALNS ;
DR   Q5PG48, BIOB_SALPA ;  A9MTI8, BIOB_SALPB ;  C0PWY2, BIOB_SALPC ;
DR   B5BC31, BIOB_SALPK ;  Q2S4I8, BIOB_SALRD ;  B4TQT9, BIOB_SALSV ;
DR   Q8Z893, BIOB_SALTI ;  A4X585, BIOB_SALTO ;  P12678, BIOB_SALTY ;
DR   O59778, BIOB_SCHPO ;  P36569, BIOB_SERMA ;  A8GBC5, BIOB_SERP5 ;
DR   A1S5I9, BIOB_SHEAM ;  B8EAJ2, BIOB_SHEB2 ;  A3D3F2, BIOB_SHEB5 ;
DR   A6WM55, BIOB_SHEB8 ;  A9KY60, BIOB_SHEB9 ;  Q12NN4, BIOB_SHEDO ;
DR   Q084I8, BIOB_SHEFN ;  B0TJN8, BIOB_SHEHH ;  A3QDN8, BIOB_SHELP ;
DR   Q8EDK6, BIOB_SHEON ;  A8H3I7, BIOB_SHEPA ;  A4Y7Y3, BIOB_SHEPC ;
DR   B8CQY2, BIOB_SHEPW ;  A0KY79, BIOB_SHESA ;  A8FX10, BIOB_SHESH ;
DR   Q0HHN7, BIOB_SHESM ;  Q0HTY9, BIOB_SHESR ;  A1RIK5, BIOB_SHESW ;
DR   B1KPJ7, BIOB_SHEWM ;  B2TVF5, BIOB_SHIB3 ;  Q324B7, BIOB_SHIBS ;
DR   Q32I44, BIOB_SHIDS ;  Q0T6I5, BIOB_SHIF8 ;  Q83S46, BIOB_SHIFL ;
DR   Q3Z409, BIOB_SHISS ;  Q2NUJ7, BIOB_SODGM ;  A9EXH2, BIOB_SORC5 ;
DR   Q1GTT5, BIOB_SPHAL ;  A7X669, BIOB_STAA1 ;  A6U4F5, BIOB_STAA2 ;
DR   Q2FE72, BIOB_STAA3 ;  Q2FVJ7, BIOB_STAA8 ;  A5IVK5, BIOB_STAA9 ;
DR   Q2YVY6, BIOB_STAAB ;  Q5HDC9, BIOB_STAAC ;  A6QJR4, BIOB_STAAE ;
DR   Q99RK7, BIOB_STAAM ;  Q7A3R9, BIOB_STAAN ;  Q6GE08, BIOB_STAAR ;
DR   Q6G6P6, BIOB_STAAS ;  A8YYH5, BIOB_STAAT ;  Q7A018, BIOB_STAAW ;
DR   B9DKN5, BIOB_STACT ;  Q5HKJ7, BIOB_STAEQ ;  Q8CQB3, BIOB_STAES ;
DR   Q4L9U7, BIOB_STAHJ ;  Q3K2Q5, BIOB_STRA1 ;  Q8E6Q1, BIOB_STRA3 ;
DR   Q8E197, BIOB_STRA5 ;  Q826T2, BIOB_STRAW ;  Q9FCC3, BIOB_STRCO ;
DR   B1W5F4, BIOB_STRGG ;  B4SM81, BIOB_STRM5 ;  B2FLM4, BIOB_STRMK ;
DR   Q30U81, BIOB_SULDN ;  A6Q6D8, BIOB_SULNB ;  B2V8G9, BIOB_SULSY ;
DR   Q2LY09, BIOB_SYNAS ;  Q3A4K3, BIOB_SYNC1 ;  Q31R68, BIOB_SYNE7 ;
DR   A0LJA8, BIOB_SYNFM ;  Q2JRI4, BIOB_SYNJA ;  B1XNE1, BIOB_SYNP2 ;
DR   Q5N332, BIOB_SYNP6 ;  A5GLZ1, BIOB_SYNPW ;  A5GS37, BIOB_SYNR3 ;
DR   Q0IBC8, BIOB_SYNS3 ;  Q3AX82, BIOB_SYNS9 ;  Q3AJ51, BIOB_SYNSC ;
DR   P73538, BIOB_SYNY3 ;  B9KBR9, BIOB_THENN ;  A5IK57, BIOB_THEP1 ;
DR   Q72L21, BIOB_THET2 ;  Q5SKN6, BIOB_THET8 ;  Q8DL38, BIOB_THEVB ;
DR   B5YK85, BIOB_THEYD ;  Q3SLY0, BIOB_THIDA ;  B8GTH4, BIOB_THISH ;
DR   Q10YQ3, BIOB_TRIEI ;  B3E599, BIOB_TRIL1 ;  Q3M4U9, BIOB_TRIV2 ;
DR   A5CWW0, BIOB_VESOH ;  B7VH16, BIOB_VIBA3 ;  A5F2H3, BIOB_VIBC3 ;
DR   A7MX36, BIOB_VIBCB ;  Q9KSZ4, BIOB_VIBCH ;  Q87QN6, BIOB_VIBPA ;
DR   Q8D8M9, BIOB_VIBVU ;  Q7MLV0, BIOB_VIBVY ;  Q8D2A1, BIOB_WIGBR ;
DR   Q7M8P7, BIOB_WOLSU ;  Q8PQD7, BIOB_XANAC ;  Q3BYM9, BIOB_XANC5 ;
DR   Q4UZN8, BIOB_XANC8 ;  B0RMR2, BIOB_XANCB ;  Q8PDF0, BIOB_XANCP ;
DR   Q2P8F3, BIOB_XANOM ;  B2SS67, BIOB_XANOP ;  Q5H5R1, BIOB_XANOR ;
DR   A7IEC3, BIOB_XANP2 ;  B2I672, BIOB_XYLF2 ;  Q9PH80, BIOB_XYLFA ;
DR   B0U2A0, BIOB_XYLFM ;  Q87F85, BIOB_XYLFT ;  P32451, BIOB_YEAST ;
DR   A1JS69, BIOB_YERE8 ;  A7FKM9, BIOB_YERP3 ;  Q1C947, BIOB_YERPA ;
DR   B2K8T0, BIOB_YERPB ;  Q7CH65, BIOB_YERPE ;  A9R3C8, BIOB_YERPG ;
DR   Q1CFQ3, BIOB_YERPN ;  A4TNQ6, BIOB_YERPP ;  Q66D67, BIOB_YERPS ;
DR   B1JSS4, BIOB_YERPY ;  Q5NRD6, BIOB_ZYMMO ;
//