ID   2.8.1.8
DE   lipoyl synthase.
AN   lipoate synthase.
CA   [[Fe-S] cluster scaffold protein carrying a second [4Fe-4S](2+) cluster]
CA   + 4 H(+) + N(6)-octanoyl-L-lysyl-[protein] + 2 oxidized [2Fe-2S]-
CA   [ferredoxin] + 2 S-adenosyl-L-methionine = (R)-N(6)-dihydrolipoyl-L-
CA   lysyl-[protein] + 2 5'-deoxyadenosine + [[Fe-S] cluster scaffold protein]
CA   + 4 Fe(3+) + 2 hydrogen sulfide + 2 L-methionine + 2 reduced [2Fe-2S]-
CA   [ferredoxin].
CC   -!- This enzyme catalyzes the final step in the de novo biosynthesis of
CC       the lipoyl cofactor, the attachment of two sulfhydryl groups to C6
CC       and C8 of a pendant octanoyl chain.
CC   -!- It is a member of the 'AdoMet radical' (radical SAM) family,
CC       all members of which produce the 5'-deoxyadenosin-5'-yl radical and
CC       methionine from AdoMet (S-adenosylmethionine) by the addition of an
CC       electron from an iron-sulfur center.
CC   -!- The enzyme contains two [4Fe-4S] clusters.
CC   -!- The first cluster produces the radicals, which are converted into
CC       5'-deoxyadenosine when they abstract hydrogen atoms from C6 and C8,
CC       respectively, leaving reactive radicals at these positions that
CC       interact with sulfur atoms within the second (auxiliary) cluster.
CC   -!- Having donated two sulfur atoms, the auxiliary cluster is degraded
CC       during catalysis, but is regenerated immediately by the transfer of a
CC       new cluster from iron-sulfur cluster carrier proteins.
CC   -!- Lipoylation is essential for the function of several key enzymes
CC       involved in oxidative metabolism, as it converts apoprotein into the
CC       biologically active holoprotein.
CC   -!- Examples of such lipoylated proteins include pyruvate dehydrogenase
CC       (E2 domain), 2-oxoglutarate dehydrogenase (E2 domain), the branched-
CC       chain 2-oxoacid dehydrogenases and the glycine cleavage system (H
CC       protein).
CC   -!- An alternative lipoylation pathway involves EC 6.3.1.20, which can
CC       lipoylate apoproteins using exogenous lipoic acid (or its analogs).
DR   B4IUG3, LIAS1_DROYA;  Q3LSN4, LIAS1_PEA  ;  B4PF83, LIAS2_DROYA;
DR   Q3LSN5, LIAS2_PEA  ;  Q16W22, LIAS_AEDAE ;  Q9ZWT1, LIAS_ARATH ;
DR   Q5BIP7, LIAS_BOVIN ;  C3Y3G4, LIAS_BRAFL ;  A8PF69, LIAS_BRUMA ;
DR   Q21452, LIAS_CAEEL ;  A8JGF7, LIAS_CHLRE ;  B0WAU6, LIAS_CULQU ;
DR   Q6PHG4, LIAS_DANRE ;  B3M996, LIAS_DROAN ;  B3NIL9, LIAS_DROER ;
DR   B4J3F3, LIAS_DROGR ;  Q7JQW6, LIAS_DROME ;  B4KYY0, LIAS_DROMO ;
DR   Q2LYK1, LIAS_DROPS ;  B4IAA7, LIAS_DROSE ;  B4MXR6, LIAS_DROWI ;
DR   O43766, LIAS_HUMAN ;  B8A031, LIAS_MAIZE ;  B7FM45, LIAS_MEDTR ;
DR   Q99M04, LIAS_MOUSE ;  A7TDI2, LIAS_NEMVE ;  A2XU53, LIAS_ORYSI ;
DR   Q7XRF1, LIAS_ORYSJ ;  A4RZ86, LIAS_OSTLU ;  A9NNH7, LIAS_PICSI ;
DR   B9H5L9, LIAS_POPTR ;  Q5XIH4, LIAS_RAT   ;  B9RW49, LIAS_RICCO ;
DR   C4PZQ3, LIAS_SCHMA ;  C5Y9R0, LIAS_SORBI ;  B3SBB5, LIAS_TRIAD ;
DR   A5CB81, LIAS_VITVI ;  Q6GQ48, LIAS_XENLA ;  Q89LR6, LIPA1_BRADU;
DR   Q7NLU2, LIPA1_GLOVI;  Q8YWC1, LIPA1_NOSS1;  Q7U4D9, LIPA1_PARMW;
DR   B7FRU7, LIPA1_PHATC;  Q7V9Z9, LIPA1_PROMA;  Q7V507, LIPA1_PROMM;
DR   Q7UZY1, LIPA1_PROMP;  P72980, LIPA1_SYNY3;  Q8DL83, LIPA1_THEVB;
DR   Q4DC43, LIPA1_TRYCC;  Q89NW6, LIPA2_BRADU;  Q7NFJ9, LIPA2_GLOVI;
DR   Q8YXD1, LIPA2_NOSS1;  Q7U7Q2, LIPA2_PARMW;  B7G3Y9, LIPA2_PHATC;
DR   Q7VBJ3, LIPA2_PROMA;  Q7V6S0, LIPA2_PROMM;  Q7V0Z8, LIPA2_PROMP;
DR   P73572, LIPA2_SYNY3;  Q8DLC2, LIPA2_THEVB;  Q4DYL7, LIPA2_TRYCC;
DR   A0LTD9, LIPA_ACIC1 ;  A5G2D2, LIPA_ACICJ ;  B9MB93, LIPA_ACIET ;
DR   B7J7N7, LIPA_ACIF2 ;  B5EMR4, LIPA_ACIF5 ;  A1W2S7, LIPA_ACISJ ;
DR   A3N2P1, LIPA_ACTP2 ;  B3H2J0, LIPA_ACTP7 ;  B0BRR9, LIPA_ACTPJ ;
DR   A6VM79, LIPA_ACTSZ ;  A0KNA3, LIPA_AERHH ;  Q9Y9E3, LIPA_AERPE ;
DR   A4SJV5, LIPA_AERS4 ;  B6JDY1, LIPA_AFIC5 ;  Q8UFG1, LIPA_AGRFC ;
DR   B9JEZ6, LIPA_AGRRK ;  C0NXP6, LIPA_AJECG ;  C6HLY2, LIPA_AJECH ;
DR   C5GPL2, LIPA_AJEDR ;  Q0VN36, LIPA_ALCBS ;  Q5E6V9, LIPA_ALIF1 ;
DR   B5FBJ6, LIPA_ALIFM ;  B6EIF3, LIPA_ALISL ;  Q5WDS6, LIPA_ALKCK ;
DR   Q0A8A4, LIPA_ALKEH ;  A6TWC9, LIPA_ALKMQ ;  B9JW84, LIPA_ALLAM ;
DR   Q2IIW6, LIPA_ANADE ;  A7HBU9, LIPA_ANADF ;  Q5PAD4, LIPA_ANAMM ;
DR   Q2GKX7, LIPA_ANAPZ ;  O67368, LIPA_AQUAE ;  Q5P4B8, LIPA_AROAE ;
DR   C5FZJ2, LIPA_ARTOC ;  A1CJC4, LIPA_ASPCL ;  B0XYY2, LIPA_ASPFC ;
DR   B8NUL8, LIPA_ASPFN ;  Q4WWP1, LIPA_ASPFU ;  A5ABM5, LIPA_ASPNC ;
DR   Q2U4H2, LIPA_ASPOR ;  A8I4L8, LIPA_AZOC5 ;  A1K1U7, LIPA_AZOSB ;
DR   C1DMR1, LIPA_AZOVD ;  C3PDK2, LIPA_BACAA ;  C3LCA6, LIPA_BACAC ;
DR   A0RKF7, LIPA_BACAH ;  Q81XM8, LIPA_BACAN ;  B7JDM3, LIPA_BACC0 ;
DR   Q72YB2, LIPA_BACC1 ;  B7IMZ7, LIPA_BACC2 ;  C1EY56, LIPA_BACC3 ;
DR   B7HCZ6, LIPA_BACC4 ;  B7HUW3, LIPA_BACC7 ;  A7GUG3, LIPA_BACCN ;
DR   B9J3H2, LIPA_BACCQ ;  Q816A0, LIPA_BACCR ;  Q631Z7, LIPA_BACCZ ;
DR   Q5LGU6, LIPA_BACFN ;  Q64XQ0, LIPA_BACFR ;  Q6HBT4, LIPA_BACHK ;
DR   A9VNX6, LIPA_BACMK ;  A8FH34, LIPA_BACP2 ;  O32129, LIPA_BACSU ;
DR   Q8A029, LIPA_BACTN ;  A7Z8E8, LIPA_BACVZ ;  A1USA0, LIPA_BARBK ;
DR   Q6G401, LIPA_BARHE ;  Q6G166, LIPA_BARQU ;  A9IS79, LIPA_BART1 ;
DR   Q1LTM3, LIPA_BAUCH ;  B2IB58, LIPA_BEII9 ;  C5C4Y6, LIPA_BEUC1 ;
DR   C5JVC1, LIPA_BLAGS ;  Q2L1D8, LIPA_BORA1 ;  Q7WR00, LIPA_BORBR ;
DR   Q7W222, LIPA_BORPA ;  Q7W0K8, LIPA_BORPE ;  A5EIM5, LIPA_BRASB ;
DR   A4YUR5, LIPA_BRASO ;  B2S5X5, LIPA_BRUA1 ;  Q2YPV8, LIPA_BRUA2 ;
DR   A6X0M7, LIPA_BRUA4 ;  Q57D15, LIPA_BRUAB ;  A9M5D7, LIPA_BRUC2 ;
DR   C0RJ95, LIPA_BRUMB ;  P65281, LIPA_BRUME ;  A5VQP8, LIPA_BRUO2 ;
DR   B0CGS4, LIPA_BRUSI ;  P65282, LIPA_BRUSU ;  B8D962, LIPA_BUCA5 ;
DR   P57357, LIPA_BUCAI ;  Q8K9Q2, LIPA_BUCAP ;  B8D7G6, LIPA_BUCAT ;
DR   Q89AL7, LIPA_BUCBP ;  Q057Q7, LIPA_BUCCC ;  A3MR17, LIPA_BURM7 ;
DR   A2S5Y9, LIPA_BURM9 ;  Q62N16, LIPA_BURMA ;  A1V016, LIPA_BURMS ;
DR   A3NQX6, LIPA_BURP0 ;  Q3JWL1, LIPA_BURP1 ;  A3N576, LIPA_BURP6 ;
DR   Q9EYP3, LIPA_BURPS ;  Q2T1K5, LIPA_BURTA ;  B9MQ24, LIPA_CALBD ;
DR   Q8R9E1, LIPA_CALS4 ;  A4XHV2, LIPA_CALS8 ;  P0CH67, LIPA_CANAL ;
DR   P0CH68, LIPA_CANAW ;  B9WFS9, LIPA_CANDC ;  Q6FPY0, LIPA_CANGA ;
DR   C5M276, LIPA_CANTT ;  Q9A7I8, LIPA_CAUVC ;  B8GW82, LIPA_CAUVN ;
DR   A3PJL9, LIPA_CERS1 ;  Q3J2P4, LIPA_CERS4 ;  A4WRC8, LIPA_CERS5 ;
DR   B9KSE2, LIPA_CERSK ;  Q11HV6, LIPA_CHESB ;  A9WEM1, LIPA_CHLAA ;
DR   Q5L4V4, LIPA_CHLAB ;  B8G782, LIPA_CHLAD ;  Q3ARP5, LIPA_CHLCH ;
DR   Q821K6, LIPA_CHLCV ;  Q256D6, LIPA_CHLFF ;  B3ECK5, LIPA_CHLL2 ;
DR   Q3B3Y5, LIPA_CHLL3 ;  Q9PJI2, LIPA_CHLMU ;  B3QNE9, LIPA_CHLP8 ;
DR   A1BFY3, LIPA_CHLPD ;  A4SEG3, LIPA_CHLPM ;  Q9Z774, LIPA_CHLPN ;
DR   B9LM70, LIPA_CHLSY ;  B0B8D2, LIPA_CHLT2 ;  Q3KLD9, LIPA_CHLTA ;
DR   B0BA11, LIPA_CHLTB ;  Q8KDH2, LIPA_CHLTE ;  O84562, LIPA_CHLTR ;
DR   A0M4W4, LIPA_CHRFK ;  Q7NTF9, LIPA_CHRVO ;  B5EAX0, LIPA_CITBB ;
DR   A8AJH6, LIPA_CITK8 ;  C4YA37, LIPA_CLAL4 ;  A5CQ99, LIPA_CLAM3 ;
DR   B0RE24, LIPA_CLAMS ;  C5PIN8, LIPA_COCP7 ;  Q484R8, LIPA_COLP3 ;
DR   A8N1T1, LIPA_COPC7 ;  C3PHK6, LIPA_CORA7 ;  P61194, LIPA_CORDI ;
DR   Q8FNP4, LIPA_COREF ;  A4QFS3, LIPA_CORGB ;  Q8NNJ0, LIPA_CORGL ;
DR   Q4JWE0, LIPA_CORJK ;  C4LI04, LIPA_CORK4 ;  B1VHG8, LIPA_CORU7 ;
DR   B6J7S3, LIPA_COXB1 ;  B6IZL4, LIPA_COXB2 ;  A9KFW5, LIPA_COXBN ;
DR   A9NDX8, LIPA_COXBR ;  Q83C63, LIPA_COXBU ;  A7MNP9, LIPA_CROS8 ;
DR   P0CO59, LIPA_CRYNB ;  P0CO58, LIPA_CRYNJ ;  Q1LSC9, LIPA_CUPMC ;
DR   Q0KFE6, LIPA_CUPNH ;  Q477G5, LIPA_CUPPJ ;  B2AG37, LIPA_CUPTR ;
DR   Q6A9X0, LIPA_CUTAK ;  Q11Q84, LIPA_CYTH3 ;  B5RUV1, LIPA_DEBHA ;
DR   Q47JD5, LIPA_DECAR ;  Q1IXJ7, LIPA_DEIGD ;  Q9RWA4, LIPA_DEIRA ;
DR   A9BPT7, LIPA_DELAS ;  Q6ARK0, LIPA_DESPS ;  A4J247, LIPA_DESRM ;
DR   Q72DM4, LIPA_DESVH ;  A1VF79, LIPA_DESVV ;  A5EVQ3, LIPA_DICNV ;
DR   A7ZJ15, LIPA_ECO24 ;  B7UKR9, LIPA_ECO27 ;  B7MFQ1, LIPA_ECO45 ;
DR   B7L9H2, LIPA_ECO55 ;  P60718, LIPA_ECO57 ;  B5YQH9, LIPA_ECO5E ;
DR   B7NLY7, LIPA_ECO7I ;  B7MRR5, LIPA_ECO81 ;  B7M5F5, LIPA_ECO8A ;
DR   C4ZWB5, LIPA_ECOBW ;  A7ZXQ4, LIPA_ECOHS ;  A1A8Q3, LIPA_ECOK1 ;
DR   Q0TK45, LIPA_ECOL5 ;  P60717, LIPA_ECOL6 ;  B1IYI0, LIPA_ECOLC ;
DR   P60716, LIPA_ECOLI ;  B7N9N3, LIPA_ECOLU ;  B6I137, LIPA_ECOSE ;
DR   B1LKL9, LIPA_ECOSM ;  Q1RET3, LIPA_ECOUT ;  C5BGD9, LIPA_EDWI9 ;
DR   Q3YRT2, LIPA_EHRCJ ;  Q2GGX7, LIPA_EHRCR ;  Q5FFK4, LIPA_EHRRG ;
DR   Q5HB02, LIPA_EHRRW ;  Q5AQE4, LIPA_EMENI ;  A4W814, LIPA_ENT38 ;
DR   Q74ZH6, LIPA_EREGS ;  B2VBK1, LIPA_ERWT9 ;  Q2NAD7, LIPA_ERYLH ;
DR   B7LLI3, LIPA_ESCF3 ;  A5FNF9, LIPA_FLAJ1 ;  A6GZL9, LIPA_FLAPJ ;
DR   Q0RFE8, LIPA_FRAAA ;  Q2J897, LIPA_FRACC ;  B0TZD6, LIPA_FRAP2 ;
DR   Q14IH3, LIPA_FRAT1 ;  A7NBV0, LIPA_FRATF ;  Q2A3R2, LIPA_FRATH ;
DR   B2SH72, LIPA_FRATM ;  A0Q6Q2, LIPA_FRATN ;  Q0BM68, LIPA_FRATO ;
DR   Q5NH21, LIPA_FRATT ;  A4IY90, LIPA_FRATW ;  C7Z527, LIPA_FUSV7 ;
DR   B9M4F4, LIPA_GEODF ;  Q5KVM7, LIPA_GEOKA ;  Q39QW1, LIPA_GEOMG ;
DR   P61196, LIPA_GEOSL ;  C6DYX9, LIPA_GEOSM ;  C5D7H5, LIPA_GEOSW ;
DR   A4ISG5, LIPA_GEOTN ;  A5GCS6, LIPA_GEOUR ;  B8F679, LIPA_GLAP5 ;
DR   Q5FNM1, LIPA_GLUOX ;  Q0BSW6, LIPA_GRABC ;  Q7VKB1, LIPA_HAEDU ;
DR   Q4QPL8, LIPA_HAEI8 ;  A5UBB2, LIPA_HAEIE ;  A5UFJ8, LIPA_HAEIG ;
DR   P44463, LIPA_HAEIN ;  Q2SA38, LIPA_HAHCH ;  Q9K7C9, LIPA_HALH5 ;
DR   A1WT98, LIPA_HALHL ;  B9LR22, LIPA_HALLT ;  B0R7C4, LIPA_HALS3 ;
DR   Q9HN78, LIPA_HALSA ;  A4G9C6, LIPA_HERAR ;  Q0I1H8, LIPA_HISS1 ;
DR   B0UVP7, LIPA_HISS2 ;  Q31F42, LIPA_HYDCU ;  Q5QYE5, LIPA_IDILO ;
DR   A6T345, LIPA_JANMA ;  A8Z609, LIPA_KARMG ;  A6WD63, LIPA_KINRD ;
DR   B5XZS6, LIPA_KLEP3 ;  A6T689, LIPA_KLEP7 ;  Q6CLS2, LIPA_KLULA ;
DR   B2GJ88, LIPA_KOCRD ;  C4QYF2, LIPA_KOMPG ;  Q1II13, LIPA_KORVE ;
DR   B0CQH8, LIPA_LACBS ;  C5DGZ5, LIPA_LACTC ;  C1D5T3, LIPA_LARHH ;
DR   Q5X703, LIPA_LEGPA ;  A5IGG3, LIPA_LEGPC ;  Q5ZXI6, LIPA_LEGPH ;
DR   Q5WYF5, LIPA_LEGPL ;  A4H9Z3, LIPA_LEIBR ;  A4HY57, LIPA_LEIIN ;
DR   Q4QDI6, LIPA_LEIMA ;  Q6AFG7, LIPA_LEIXX ;  B0SGV6, LIPA_LEPBA ;
DR   Q04T63, LIPA_LEPBJ ;  Q051I5, LIPA_LEPBL ;  B0SQ03, LIPA_LEPBP ;
DR   B1XX30, LIPA_LEPCP ;  Q72RU2, LIPA_LEPIC ;  Q8F3V7, LIPA_LEPIN ;
DR   A5E450, LIPA_LODEL ;  B9EAJ9, LIPA_MACCJ ;  A0L509, LIPA_MAGMM ;
DR   Q65RH7, LIPA_MANSM ;  Q0APQ9, LIPA_MARMM ;  A1U380, LIPA_MARN8 ;
DR   Q0W150, LIPA_METAR ;  B7KRC9, LIPA_METC4 ;  Q60CJ6, LIPA_METCA ;
DR   A9W6I4, LIPA_METEP ;  Q1GYC1, LIPA_METFK ;  B8IDD6, LIPA_METNO ;
DR   B1ZEL4, LIPA_METPB ;  B1LWN4, LIPA_METRJ ;  B8EJU1, LIPA_METSB ;
DR   C5CCN0, LIPA_MICLC ;  Q2RHM6, LIPA_MOOTA ;  A0QEY6, LIPA_MYCA1 ;
DR   P65284, LIPA_MYCBO ;  A1KKR0, LIPA_MYCBP ;  C1AQD3, LIPA_MYCBT ;
DR   A4TBK7, LIPA_MYCGI ;  B8ZQJ9, LIPA_MYCLB ;  O32962, LIPA_MYCLE ;
DR   B2HHL4, LIPA_MYCMM ;  P61197, LIPA_MYCPA ;  A0R075, LIPA_MYCS2 ;
DR   A3Q1S8, LIPA_MYCSJ ;  A1UIB4, LIPA_MYCSK ;  Q1B6R1, LIPA_MYCSS ;
DR   A5U4P6, LIPA_MYCTA ;  P9WK90, LIPA_MYCTO ;  P9WK91, LIPA_MYCTU ;
DR   A0PNH7, LIPA_MYCUA ;  Q1D4N0, LIPA_MYXXD ;  Q3IU11, LIPA_NATPD ;
DR   Q5F8I0, LIPA_NEIG1 ;  B4RLK9, LIPA_NEIG2 ;  A9LZ95, LIPA_NEIM0 ;
DR   Q9JUC8, LIPA_NEIMA ;  Q9JZA5, LIPA_NEIMB ;  A1D855, LIPA_NEOFI ;
DR   Q2GE84, LIPA_NEOSM ;  Q7SF84, LIPA_NEUCR ;  Q0AI05, LIPA_NITEC ;
DR   Q82UJ5, LIPA_NITEU ;  Q1QMA2, LIPA_NITHX ;  Q2Y7I9, LIPA_NITMU ;
DR   Q3J7W4, LIPA_NITOC ;  Q3SSP1, LIPA_NITWN ;  Q5YZ59, LIPA_NOCFA ;
DR   A1SJ19, LIPA_NOCSJ ;  Q2G712, LIPA_NOVAD ;  Q8ERL8, LIPA_OCEIH ;
DR   Q30XT6, LIPA_OLEA2 ;  A5CCM4, LIPA_ORITB ;  B3CQP5, LIPA_ORITI ;
DR   C1H594, LIPA_PARBA ;  C1GFM3, LIPA_PARBD ;  C0SDG9, LIPA_PARBP ;
DR   A1TJ31, LIPA_PARC0 ;  A6LE09, LIPA_PARD8 ;  A1B1T3, LIPA_PARDP ;
DR   A7HXW0, LIPA_PARL1 ;  Q6MEX3, LIPA_PARUW ;  P57978, LIPA_PASMU ;
DR   B1X4X1, LIPA_PAUCH ;  Q6D7M8, LIPA_PECAS ;  C6DBV6, LIPA_PECCP ;
DR   B4SHB4, LIPA_PELPB ;  A1AMT5, LIPA_PELPD ;  Q4FM35, LIPA_PELUB ;
DR   B6HFQ1, LIPA_PENRW ;  Q0V6U4, LIPA_PHANO ;  B4RBV1, LIPA_PHEZH ;
DR   Q7N767, LIPA_PHOLL ;  Q6LN87, LIPA_PHOPR ;  A6L1U8, LIPA_PHOV8 ;
DR   D0NP70, LIPA_PHYIT ;  A5DGI1, LIPA_PICGU ;  A3GGJ5, LIPA_PICST ;
DR   Q6L1L7, LIPA_PICTO ;  Q8IDQ0, LIPA_PLAF7 ;  B3L8F2, LIPA_PLAKH ;
DR   A5K883, LIPA_PLAVS ;  Q7RBD6, LIPA_PLAYO ;  B2AT43, LIPA_PODAN ;
DR   A1VIT9, LIPA_POLNA ;  B2RKU2, LIPA_PORG3 ;  Q7MWT4, LIPA_PORGI ;
DR   A8G714, LIPA_PROM2 ;  B4EV01, LIPA_PROMH ;  Q48DM6, LIPA_PSE14 ;
DR   Q15VL3, LIPA_PSEA6 ;  A6V0B4, LIPA_PSEA7 ;  B7V9C1, LIPA_PSEA8 ;
DR   Q02SG3, LIPA_PSEAB ;  Q9HX25, LIPA_PSEAE ;  Q1I4G1, LIPA_PSEE4 ;
DR   C3K2L8, LIPA_PSEFS ;  A4XYX3, LIPA_PSEMY ;  A5W9I5, LIPA_PSEP1 ;
DR   Q3K6A4, LIPA_PSEPF ;  Q88DM5, LIPA_PSEPK ;  B1J144, LIPA_PSEPW ;
DR   Q87VW7, LIPA_PSESM ;  Q3IJ81, LIPA_PSET1 ;  Q4ZN84, LIPA_PSEU2 ;
DR   Q4FTQ5, LIPA_PSYA2 ;  Q1QCS6, LIPA_PSYCK ;  A1SZ17, LIPA_PSYIN ;
DR   A5WDV8, LIPA_PSYWF ;  Q8ZUR9, LIPA_PYRAE ;  A4WK38, LIPA_PYRAR ;
DR   A3MW09, LIPA_PYRCJ ;  B2WBE8, LIPA_PYRTR ;  Q8Y2L3, LIPA_RALN1 ;
DR   B2UE01, LIPA_RALPJ ;  B3PYS0, LIPA_RHIE6 ;  Q2K8V9, LIPA_RHIEC ;
DR   Q1MH26, LIPA_RHIL3 ;  Q98MY2, LIPA_RHILO ;  B5ZNB1, LIPA_RHILW ;
DR   Q92Q94, LIPA_RHIME ;  A5V2U6, LIPA_RHIWR ;  Q7UH37, LIPA_RHOBA ;
DR   B6IQ36, LIPA_RHOCS ;  Q2IW20, LIPA_RHOP2 ;  Q07MZ5, LIPA_RHOP5 ;
DR   P61198, LIPA_RHOPA ;  Q214R4, LIPA_RHOPB ;  Q137C6, LIPA_RHOPS ;
DR   B3QIL2, LIPA_RHOPT ;  Q2RT68, LIPA_RHORT ;  C3PLL8, LIPA_RICAE ;
DR   A8GPR5, LIPA_RICAH ;  A8GUH3, LIPA_RICB8 ;  Q1RGX4, LIPA_RICBR ;
DR   A8EZU2, LIPA_RICCK ;  Q92GH8, LIPA_RICCN ;  Q4UK97, LIPA_RICFE ;
DR   A8F2M4, LIPA_RICM5 ;  O05959, LIPA_RICPR ;  C4K1I0, LIPA_RICPU ;
DR   B0BV26, LIPA_RICRO ;  A8GTI8, LIPA_RICRS ;  Q68W08, LIPA_RICTY ;
DR   A5US48, LIPA_ROSS1 ;  Q1AT13, LIPA_RUBXD ;  Q1GGW2, LIPA_RUEST ;
DR   A1AWI8, LIPA_RUTMC ;  A4FA70, LIPA_SACEN ;  Q97U63, LIPA_SACS2 ;
DR   B5EZ72, LIPA_SALA4 ;  A9MKE4, LIPA_SALAR ;  Q57RU3, LIPA_SALCH ;
DR   B5FMM8, LIPA_SALDC ;  B5QVN4, LIPA_SALEP ;  B5R7Y1, LIPA_SALG2 ;
DR   B4TAI5, LIPA_SALHS ;  B4SYJ0, LIPA_SALNS ;  Q5PM97, LIPA_SALPA ;
DR   A9MV74, LIPA_SALPB ;  C0PW62, LIPA_SALPC ;  B5BCG1, LIPA_SALPK ;
DR   B4TPA3, LIPA_SALSV ;  Q8Z8I3, LIPA_SALTI ;  Q8ZR04, LIPA_SALTY ;
DR   B6K4J2, LIPA_SCHJY ;  O13642, LIPA_SCHPO ;  A7EV21, LIPA_SCLS1 ;
DR   A8GB09, LIPA_SERP5 ;  A1S8U1, LIPA_SHEAM ;  B8E4W4, LIPA_SHEB2 ;
DR   A3D7P9, LIPA_SHEB5 ;  A6WRL2, LIPA_SHEB8 ;  A9L014, LIPA_SHEB9 ;
DR   Q12QX1, LIPA_SHEDO ;  Q087L5, LIPA_SHEFN ;  B0TR57, LIPA_SHEHH ;
DR   A3QH60, LIPA_SHELP ;  Q8EHQ6, LIPA_SHEON ;  A8H7D5, LIPA_SHEPA ;
DR   A4Y9G2, LIPA_SHEPC ;  B8CSH7, LIPA_SHEPW ;  A0KTV4, LIPA_SHESA ;
DR   A8FZ23, LIPA_SHESH ;  Q0HLK3, LIPA_SHESM ;  Q0HXV7, LIPA_SHESR ;
DR   A1RGT2, LIPA_SHESW ;  B1KDX3, LIPA_SHEWM ;  B2TTI9, LIPA_SHIB3 ;
DR   Q324R5, LIPA_SHIBS ;  Q32IV2, LIPA_SHIDS ;  Q0T6N8, LIPA_SHIF8 ;
DR   P60719, LIPA_SHIFL ;  Q3Z4G4, LIPA_SHISS ;  A6U8F5, LIPA_SINMW ;
DR   Q2NUV8, LIPA_SODGM ;  A9FD62, LIPA_SORC5 ;  D1Z4I6, LIPA_SORMK ;
DR   Q1GTM7, LIPA_SPHAL ;  A7X0C7, LIPA_STAA1 ;  A6U030, LIPA_STAA2 ;
DR   Q2FIE9, LIPA_STAA3 ;  Q2FZX4, LIPA_STAA8 ;  A5IRA1, LIPA_STAA9 ;
DR   Q2YWR5, LIPA_STAAB ;  Q5HHG0, LIPA_STAAC ;  A6QFD6, LIPA_STAAE ;
DR   P65285, LIPA_STAAM ;  P65286, LIPA_STAAN ;  Q6GIG3, LIPA_STAAR ;
DR   Q6GB01, LIPA_STAAS ;  A8Z1I3, LIPA_STAAT ;  P65287, LIPA_STAAW ;
DR   B9DIX8, LIPA_STACT ;  Q5HQN7, LIPA_STAEQ ;  Q8CPW4, LIPA_STAES ;
DR   Q4L4T8, LIPA_STAHJ ;  Q49W64, LIPA_STAS1 ;  Q82AP7, LIPA_STRAW ;
DR   Q9S2P2, LIPA_STRCO ;  B1VZM3, LIPA_STRGG ;  B4SJ16, LIPA_STRM5 ;
DR   B2FUS8, LIPA_STRMK ;  A4VQZ6, LIPA_STUS1 ;  Q4JBV4, LIPA_SULAC ;
DR   Q67MF5, LIPA_SYMTH ;  Q57390, LIPA_SYNC1 ;  A5GW06, LIPA_SYNR3 ;
DR   B6QSZ4, LIPA_TALMQ ;  B8MLU5, LIPA_TALSN ;  Q47R88, LIPA_THEFY ;
DR   Q72GV1, LIPA_THET2 ;  Q5SLQ4, LIPA_THET8 ;  Q3SM23, LIPA_THIDA ;
DR   B8GMV6, LIPA_THISH ;  C4LCC5, LIPA_TOLAT ;  Q86G50, LIPA_TOXGO ;
DR   P61199, LIPA_TREDE ;  B3E6X0, LIPA_TRIL1 ;  Q83NN8, LIPA_TROW8 ;
DR   Q83MU9, LIPA_TROWT ;  Q388A7, LIPA_TRYB2 ;  D0A0G6, LIPA_TRYB9 ;
DR   C4JE77, LIPA_UNCRE ;  C5CP21, LIPA_VARPS ;  A1WF48, LIPA_VEREI ;
DR   A5CWR6, LIPA_VESOH ;  B7VKE6, LIPA_VIBA3 ;  A7MY96, LIPA_VIBC1 ;
DR   A5F2Y0, LIPA_VIBC3 ;  Q9KTF9, LIPA_VIBCH ;  C3LTJ1, LIPA_VIBCM ;
DR   Q87RR1, LIPA_VIBPA ;  Q8DFD1, LIPA_VIBVU ;  Q7MN17, LIPA_VIBVY ;
DR   Q8D325, LIPA_WIGBR ;  P61200, LIPA_WOLPM ;  B3CP16, LIPA_WOLPP ;
DR   Q5GSY2, LIPA_WOLTR ;  C0R2Q4, LIPA_WOLWR ;  Q8PPL8, LIPA_XANAC ;
DR   Q3BXQ3, LIPA_XANC5 ;  Q4UYT2, LIPA_XANC8 ;  B0RNP9, LIPA_XANCB ;
DR   Q8P590, LIPA_XANCP ;  Q2NYZ2, LIPA_XANOM ;  Q5GVR7, LIPA_XANOR ;
DR   A7IM78, LIPA_XANP2 ;  B2I923, LIPA_XYLF2 ;  Q9PDW0, LIPA_XYLFA ;
DR   B0U641, LIPA_XYLFM ;  Q87DZ9, LIPA_XYLFT ;  Q6C6C6, LIPA_YARLI ;
DR   B3LJM6, LIPA_YEAS1 ;  C7GWI3, LIPA_YEAS2 ;  B5VS81, LIPA_YEAS6 ;
DR   A6ZP42, LIPA_YEAS7 ;  C8ZGV5, LIPA_YEAS8 ;  P32875, LIPA_YEAST ;
DR   A1JPR9, LIPA_YERE8 ;  A7FKY9, LIPA_YERP3 ;  Q1C507, LIPA_YERPA ;
DR   B2K874, LIPA_YERPB ;  Q8ZDH0, LIPA_YERPE ;  A9R703, LIPA_YERPG ;
DR   Q1CKR6, LIPA_YERPN ;  A4TP09, LIPA_YERPP ;  Q66DF5, LIPA_YERPS ;
DR   B1JGB7, LIPA_YERPY ;  C5DY71, LIPA_ZYGRC ;  Q9RNY7, LIPA_ZYMMO ;
DR   B6TN12, LISC1_MAIZE;  B8AA76, LISC1_ORYSI;  Q5ZAQ2, LISC1_ORYSJ;
DR   B9I666, LISC1_POPTR;  C0PN26, LISC2_MAIZE;  B8B016, LISC2_ORYSI;
DR   Q6L534, LISC2_ORYSJ;  B9N2B0, LISC2_POPTR;  Q8LEE8, LISC_ARATH ;
DR   A8I2V9, LISC_CHLRE ;  A4RW69, LISC_OSTLU ;  B9RX57, LISC_RICCO ;
DR   C5XKZ1, LISC_SORBI ;
//