ID   2.8.2.33
DE   N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase.
AN   GalNAc4S-6ST.
CA   (1) n 3'-phosphoadenylyl sulfate + dermatan 4'-sulfate = n adenosine
CA   3',5'-bisphosphate + dermatan 4',6'-bissulfate + n H(+).
CA   (2) n 3'-phosphoadenylyl sulfate + chondroitin 4'-sulfate = n adenosine
CA   3',5'-bisphosphate + chondroitin 4',6'-bissulfate + n H(+).
CC   -!- The enzyme from human transfers sulfate to position 6 of both
CC       internal residues and non-reducing terminal GalNAc 4-sulfate residues
CC       of chondroitin sulfate.
CC   -!- Oligosaccharides derived from chondroitin sulfate also serve as
CC       acceptors but chondroitin sulfate E, keratan sulfate and heparan
CC       sulfate do not.
CC   -!- Differs from EC 2.8.2.17 in being able to use both chondroitin and
CC       dermatan as effective substrates.
DR   Q7LFX5, CHSTF_HUMAN;  Q91XQ5, CHSTF_MOUSE;  Q8WTN9, CHSTF_NOTSL;
DR   Q8CHI9, CHSTF_RAT  ;
//