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ENZYME entry: EC 2.8.3.15

Accepted Name
Succinyl-CoA:(R)-benzylsuccinate CoA-transferase.
Alternative Name(s)
Benzylsuccinate CoA-transferase.
Reaction catalysed
Succinyl-CoA + (R)-2-benzylsuccinate <=> succinate + (R)-2-benzylsuccinyl-CoA
Comment(s)
  • Involved in anaerobic catabolism of toluene and is a strictly toluene-induced enzyme that catalyzes the reversible regio- and enantio-selective synthesis of (R)-2-benzylsuccinyl-CoA.
  • The enzyme from Thauera aromatica is inactive when (R)- benzylsuccinate is replaced by (S)-benzylsuccinate.
Cross-references
BRENDA2.8.3.15
EC2PDB2.8.3.15
ExplorEnz2.8.3.15
PRIAM enzyme-specific profiles2.8.3.15
KEGG Ligand Database for Enzyme Nomenclature2.8.3.15
IUBMB Enzyme Nomenclature2.8.3.15
IntEnz2.8.3.15
MEDLINEFind literature relating to 2.8.3.15
MetaCyc2.8.3.15
Rhea expert-curated reactions2.8.3.15
UniProtKB/Swiss-Prot
Q9KJF0, BBSE_THAAR;  Q9KJE9, BBSF_THAAR;  

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