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ENZYME entry: EC 2.8.3.22

Accepted Name
Succinyl-CoA--L-malate CoA-transferase.
Reaction catalysed
  • Succinyl-CoA + (S)-malate <=> succinate + (S)-malyl-CoA
  • Succinyl-CoA + (S)-citramalate <=> succinate + (S)-citramalyl-CoA
Comment(s)
  • The enzyme, purified from the bacterium Chloroflexus aurantiacus, can also accept itaconate as acceptor, with lower efficiency.
  • It is part of the 3-hydroxypropanoate cycle for carbon assimilation.
Cross-references
BRENDA2.8.3.22
EC2PDB2.8.3.22
ExplorEnz2.8.3.22
PRIAM enzyme-specific profiles2.8.3.22
KEGG Ligand Database for Enzyme Nomenclature2.8.3.22
IUBMB Enzyme Nomenclature2.8.3.22
IntEnz2.8.3.22
MEDLINEFind literature relating to 2.8.3.22
MetaCyc2.8.3.22
Rhea expert-curated reactions2.8.3.22
UniProtKB/Swiss-Prot
A9WC40, SMTA_CHLAA;  Q1KLK1, SMTA_CHLAU;  A9WC39, SMTB_CHLAA;  
Q1KLK0, SMTB_CHLAU;  

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