ENZYME entry: EC 2.8.3.24
| Accepted Name |
|---|
| (R)-2-hydroxy-4-methylpentanoate CoA-transferase.
|
| Reaction catalysed |
|---|
| 4-methylpentanoyl-CoA + (R)-2-hydroxy-4-methylpentanoate <=> 4-methylpentanoate + (R)-2-hydroxy-4-methylpentanoyl-CoA |
| Comment(s) |
|---|
- The enzyme, characterized from the bacterium Peptoclostridium
difficile, participates in an L-leucine fermentation pathway.
- The reaction proceeds via formation of a covalent anhydride
intermediate between a conserved aspartate residue and the acyl group
of the CoA thioester substrate.
|
| Cross-references |
|---|
| BRENDA | 2.8.3.24 |
| EC2PDB | 2.8.3.24 |
| ExplorEnz | 2.8.3.24 |
| PRIAM enzyme-specific profiles | 2.8.3.24 |
| KEGG Ligand Database for Enzyme Nomenclature | 2.8.3.24 |
| IUBMB Enzyme Nomenclature | 2.8.3.24 |
| IntEnz | 2.8.3.24 |
| MEDLINE | Find literature relating to 2.8.3.24 |
| MetaCyc | 2.8.3.24 |
| Rhea expert-curated reactions | 2.8.3.24 |
View entry in original ENZYME format
View entry in raw text format (no links)
All
ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 2.8.3.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.8.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-