ENZYME entry: EC 2.8.3.24
Accepted Name |
(R)-2-hydroxy-4-methylpentanoate CoA-transferase.
|
Reaction catalysed |
(R)-2-hydroxy-4-methylpentanoate + 4-methylpentanoyl-CoA <=> (R)-2-hydroxy-4-methylpentanoyl-CoA + 4-methylpentanoate |
Comment(s) |
- The enzyme, characterized from the bacterium Peptoclostridium
difficile, participates in an L-leucine fermentation pathway.
- The reaction proceeds via formation of a covalent anhydride
intermediate between a conserved aspartate residue and the acyl group
of the CoA thioester substrate.
|
Cross-references |
BRENDA | 2.8.3.24 |
EC2PDB | 2.8.3.24 |
ExplorEnz | 2.8.3.24 |
PRIAM enzyme-specific profiles | 2.8.3.24 |
KEGG Ligand Database for Enzyme Nomenclature | 2.8.3.24 |
IUBMB Enzyme Nomenclature | 2.8.3.24 |
IntEnz | 2.8.3.24 |
MEDLINE | Find literature relating to 2.8.3.24 |
MetaCyc | 2.8.3.24 |
Rhea expert-curated reactions | 2.8.3.24 |
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ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 2.8.3.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.8.-.-
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