ID 2.8.3.25 DE bile acid CoA-transferase. AN bile acid coenzyme A transferase. CA (1) cholate + lithocholoyl-CoA = choloyl-CoA + lithocholate. CA (2) cholate + deoxycholoyl-CoA = choloyl-CoA + deoxycholate. CC -!- The enzyme, characterized from the gut bacterium Clostridium CC scindens, catalyzes the last step in bile acid 7alpha- CC dehydroxylation, the removal of the CoA moiety from the products. CC -!- By using a transferase rather than hydrolase, the bacteria conserve CC the thioester bond energy, saving ATP molecules. CC -!- The enzyme has a broad substrate specificity and can use multiple CC acceptors, including allocholate, ursodeoxycholate, and beta- CC muricholate. CC -!- Formerly EC 3.1.2.26. DR P19413, BAIF_CLOSV ; B4YST4, BAIK_CLOSV ; //