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ENZYME entry: EC 2.8.3.5

Accepted Name
3-oxoacid CoA-transferase.
Alternative Name(s)
Succinyl-CoA:3-ketoacid-CoA transferase.
Reaction catalysed
Succinyl-CoA + a 3-oxo acid <=> succinate + a 3-oxoacyl-CoA
Comment(s)
  • Acetoacetate or, more slowly, 3-oxopropanoate, 3-oxopentanoate, 3-oxo-4-methylpentanoate or 3-oxohexanoate can act as acceptor.
  • Malonyl-CoA can act instead of succinyl-CoA.
Cross-references
PROSITEPDOC00980
BRENDA2.8.3.5
EC2PDB2.8.3.5
ExplorEnz2.8.3.5
PRIAM enzyme-specific profiles2.8.3.5
KEGG Ligand Database for Enzyme Nomenclature2.8.3.5
IUBMB Enzyme Nomenclature2.8.3.5
IntEnz2.8.3.5
MEDLINEFind literature relating to 2.8.3.5
MetaCyc2.8.3.5
Rhea expert-curated reactions2.8.3.5
UniProtKB/Swiss-Prot
Q9JJN4, SCO2A_MOUSE;  Q5XIJ9, SCO2A_RAT;  Q9ESL0, SCO2B_MOUSE;  
P42315, SCOA_BACSU;  Q9ZLE3, SCOA_HELPJ;  P56006, SCOA_HELPY;  
P63649, SCOA_MYCBO;  P9WPW4, SCOA_MYCTO;  P9WPW5, SCOA_MYCTU;  
B0RVK4, SCOA_XANCB;  P0C7I7, SCOA_XANCP;  P42316, SCOB_BACSU;  
Q9ZLE4, SCOB_HELPJ;  P56007, SCOB_HELPY;  P63651, SCOB_MYCBO;  
P9WPW2, SCOB_MYCTO;  P9WPW3, SCOB_MYCTU;  B0RVK3, SCOB_XANCB;  
P0C7I8, SCOB_XANCP;  P55809, SCOT1_HUMAN;  Q9D0K2, SCOT1_MOUSE;  
Q29551, SCOT1_PIG;  B2GV06, SCOT1_RAT;  Q9BYC2, SCOT2_HUMAN;  
Q09450, SCOT_CAEEL;  Q54JD9, SCOT_DICDI;  Q9W058, SCOT_DROME;  

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