A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC

Accepted Name
Acetate CoA-transferase.
Reaction catalysed
Acyl-CoA + acetate <=> a fatty acid anion + acetyl-CoA
  • The enzyme belongs to family I of CoA-transferases, which operate with a ping-pong kinetic mechanism.
  • The reaction takes place in two half-reactions and involves the formation of a CoA thioester intermediate with a glutamate residue.
  • Unlike EC, this enzyme exhibits maximal activity using acetate as the CoA acceptor.
  • Substrate range depends on the specific enzyme.
  • Typical substrates include butanoyl-CoA and pentanoyl-CoA.
PRIAM enzyme-specific profiles2.8.3.8
KEGG Ligand Database for Enzyme Nomenclature2.8.3.8
IUBMB Enzyme Nomenclature2.8.3.8
MEDLINEFind literature relating to
P76459, ATOA_ECOLI;  P44874, ATOA_HAEIN;  P76458, ATOD_ECOLI;  
P44875, ATOD_HAEIN;  Q8X5X6, YDIF_ECO57;  P37766, YDIF_ECOLI;  

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