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ENZYME

ENZYME entry: EC 2.8.5.2

PURL: https://purl.expasy.org/enzyme/EC/2.8.5.2
Accepted Name
L-cysteine S-thiosulfotransferase
Reaction catalysed
  • L-cysteinyl-[SoxY protein] + thiosulfate + 2 Fe(III)-[cytochrome c] = S-sulfosulfanyl-L-cysteinyl-[SoxY protein] + 2 Fe(II)-[cytochrome c] + 2 H(+)
  • S-sulfanyl-L-cysteinyl-[SoxY protein] + thiosulfate + 2 Fe(III)-[cytochrome c] = S-(2-sulfodisulfanyl)-L-cysteinyl-[SoxY protein] + 2 Fe(II)-[cytochrome c] + 2 H(+)
Comment(s)
  • The enzyme is part of the Sox enzyme system, which participates in a bacterial thiosulfate oxidation pathway that produces sulfate.
  • It catalyzes two reactions in the pathway - early in the pathway it attaches a thiosulfate molecule to the sulfur atom of an L-cysteine of a SoxY protein; later it transfers a second thiosulfate molecule to a sulfane group that is already attached to the same cysteine residue.
Cross-references
BRENDA2.8.5.2
EC2PDB2.8.5.2
ExplorEnz2.8.5.2
KEGG Ligand Database for Enzyme Nomenclature2.8.5.2
IUBMB Enzyme Nomenclature2.8.5.2
MEDLINEFind literature relating to 2.8.5.2
MetaCyc2.8.5.2
Rhea expert-curated reactions2.8.5.2
UniProtKB/Swiss-Prot
D3DJG4, SOXA1_HYDTTD3DJG5, SOXA2_HYDTTQ1W3E4, SOXA_ALLVI
D7A6E5, SOXA_ANCN5Q8KDM7, SOXA_CHLTEQ8RLX0, SOXA_CHLTI
Q08IS0, SOXA_HYDTEO33434, SOXA_PARPNQ9K4M4, SOXA_PSESE
Q939U1, SOXA_RHOSU

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