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ENZYME

ENZYME entry: EC 2.9.1.1

Accepted Name
L-seryl-tRNA(Sec) selenium transferase
Alternative Name(s)
cysteinyl-tRNA(Sec)-selenium transferase
cysteinyl-tRNA(Sel)-selenium transferase
L-selenocysteinyl-tRNA(Sec) synthase
L-selenocysteinyl-tRNA(Sel) synthase
selenocysteine synthase
Reaction catalysed
H(+) + L-seryl-tRNA(Sec) + selenophosphate <=> L-selenocysteinyl-tRNA(Sec) + phosphate
Comment(s)
  • Recognizes specifically tRNA(Sec)-species.
  • Binding of tRNA(Sec) also occurs in the absence of the seryl group.
  • 2-Aminoacryloyl-tRNA, bound to the enzyme as an imine with the pyridoxal phosphate, is an intermediate in the reaction.
  • Since the selenium atom replaces oxygen in serine, the product may also be referred to as L-selenoseryl-tRNA(Sel).
  • The abbreviation Sel has also been used for selenocysteine but Sec is preferred.
Cross-references
BRENDA2.9.1.1
EC2PDB2.9.1.1
ExplorEnz2.9.1.1
PRIAM enzyme-specific profiles2.9.1.1
KEGG Ligand Database for Enzyme Nomenclature2.9.1.1
IUBMB Enzyme Nomenclature2.9.1.1
IntEnz2.9.1.1
MEDLINEFind literature relating to 2.9.1.1
MetaCyc2.9.1.1
Rhea expert-curated reactions2.9.1.1
UniProtKB/Swiss-Prot
A3N2L0, SELA_ACTP2B3GYP5, SELA_ACTP7A8EV04, SELA_ALIB4
A6TQL2, SELA_ALKMQA8MHJ4, SELA_ALKOOO67140, SELA_AQUAE
Q8R8W4, SELA_CALS4A7ZBQ0, SELA_CAMC1A0RR46, SELA_CAMFF
A8FN57, SELA_CAMJ8A7H1W2, SELA_CAMJDQ9PMS2, SELA_CAMJE
A1W0Z5, SELA_CAMJJQ5HT33, SELA_CAMJRB9KDG5, SELA_CAMLR
Q3AB61, SELA_CARHZA7FXT6, SELA_CLOB1C3L3I3, SELA_CLOB6
A5I656, SELA_CLOBHC1FVV5, SELA_CLOBJB1ILX5, SELA_CLOBK
A7GHJ2, SELA_CLOBLB1KZQ3, SELA_CLOBMQ0TNJ4, SELA_CLOP1
Q8XIK2, SELA_CLOPEQ0SR63, SELA_CLOPSB1I3P6, SELA_DESAP
P56372, SELA_DESBAB8J1N0, SELA_DESDAQ6AMK5, SELA_DESPS
P61735, SELA_DESVHA7ZTD9, SELA_ECO24B7ULF0, SELA_ECO27
B7MFF5, SELA_ECO45B7L708, SELA_ECO55P0A822, SELA_ECO57
B5YW91, SELA_ECO5EB7NP97, SELA_ECO7IB7N237, SELA_ECO81
B7M3L6, SELA_ECO8AC4ZXI2, SELA_ECOBWA8A651, SELA_ECOHS
A1AHD0, SELA_ECOK1Q0TBL4, SELA_ECOL5Q8FCC1, SELA_ECOL6
B1IZK2, SELA_ECOLCP0A821, SELA_ECOLIB7NEP6, SELA_ECOLU
B6I3G5, SELA_ECOSEB1LK21, SELA_ECOSMQ1R503, SELA_ECOUT
C5BC01, SELA_EDWI9B7LTJ8, SELA_ESCF3B9LZW4, SELA_GEODF
Q39ZL4, SELA_GEOMGP61736, SELA_GEOSLA5G937, SELA_GEOUR
B8F738, SELA_GLAP5Q7VKC2, SELA_HAEDUQ4QML1, SELA_HAEI8
A5UE18, SELA_HAEIEP43910, SELA_HAEINQ7VI68, SELA_HELHP
B6JP11, SELA_HELP2Q9ZJA7, SELA_HELPJO26043, SELA_HELPY
Q0BZB0, SELA_HYPNAB5XMW1, SELA_KLEP3A6TFJ1, SELA_KLEP7
Q65Q15, SELA_MANSMC6BW42, SELA_MARSDB8ES25, SELA_METSB
Q2RFK3, SELA_MOOTAO33277, SELA_MOOTHB9L5S9, SELA_NAUPA
A1AYS1, SELA_PARDPQ9CK66, SELA_PASMUQ9S3K3, SELA_PEPAC
Q7MY02, SELA_PHOLLB4F0S0, SELA_PROMHA6VCR3, SELA_PSEA7
B7V1L9, SELA_PSEA8Q02FL3, SELA_PSEABQ9HV01, SELA_PSEAE
Q1IFP3, SELA_PSEE4A5VXT7, SELA_PSEP1B0KKB9, SELA_PSEPG
Q88QJ8, SELA_PSEPKB1J347, SELA_PSEPWP58226, SELA_RHIME
B5EX94, SELA_SALA4A9MLE0, SELA_SALARQ57IE9, SELA_SALCH
B5FLG0, SELA_SALDCB5R5B6, SELA_SALEPB5RGJ4, SELA_SALG2
B4T974, SELA_SALHSB4SWN1, SELA_SALNSQ5PLQ2, SELA_SALPA
A9MVI1, SELA_SALPBC0Q1E4, SELA_SALPCB5BHW8, SELA_SALPK
B4TZT5, SELA_SALSVQ8Z2D8, SELA_SALTIQ8ZL69, SELA_SALTY
A8G7W0, SELA_SERP5Q8EKI8, SELA_SHEONB2U5A3, SELA_SHIB3
Q31V36, SELA_SHIBSQ328Y9, SELA_SHIDSQ0SYB5, SELA_SHIF8
Q83J28, SELA_SHIFLQ3YVV3, SELA_SHISSC4XIH0, SELA_SOLM1
A4VFW8, SELA_STUS1Q30SC1, SELA_SULDNQ7M9L1, SELA_WOLSU
A1JT25, SELA_YERE8A7FP80, SELA_YERP3Q1C3H9, SELA_YERPA
B2K7H8, SELA_YERPBQ8Z9Y1, SELA_YERPEA9R4E4, SELA_YERPG
Q1CDA2, SELA_YERPNA4TGQ3, SELA_YERPPQ663U3, SELA_YERPS
B1JH26, SELA_YERPY

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.9.1.-
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