ID   3.1.1.109
DE   Iron(III) salmochelin esterase.
CA   (1) Iron(III)-[diglucosyl-enterobactin] complex + H(2)O = iron(III)-
CA   [salmochelin S2] complex.
CA   (2) Iron(III)-[monoglucosyl-enterobactin] complex + H(2)O = iron(III)-
CA   [monoglucosyl-(2,3-dihydroxybenzoylserine)(3)] complex.
CA   (3) Iron(III)-[salmochelin S2] complex + H(2)O = iron(III)-[diglucosyl-
CA   (2,3-dihydroxybenzoylserine)(2)] complex + N-(2,3-dihydroxybenzoyl)-L-
CA   serine.
CA   (4) Iron(III)-[salmochelin S2] complex + H(2)O = iron(III)-[salmochelin
CA   S1] complex + salmochelin SX.
CA   (5) Iron(III)-[monoglucosyl-(2,3-dihydroxybenzoylserine)(3)] complex +
CA   H(2)O = iron(III)-[salmochelin S1] complex + N-(2,3-dihydroxybenzoyl)-L-
CA   serine.
CA   (6) Iron(III)-[diglucosyl-(2,3-dihydroxybenzoylserine)(2)] complex +
CA   H(2)O = iron(III)-[salmochelin SX] complex + salmochelin SX.
CC   -!- This bacterial enzyme is present in pathogenic Salmonella species,
CC       uropathogenic and avian pathogenic Escherichia coli strains,
CC       and certain Klebsiella strains.
CC   -!- The enzyme acts on iron(III)-bound enterobactin and C-glucosylated
CC       derivatives known as salmochelins.
CC   -!- Unlike EC 3.1.1.107, (IroE), IroD prefers iron(III)-bound
CC       siderophores as substrates, and is assumed to act after the iron-
CC       siderophore complexes are imported into the cell.
CC   -!- It catalyzes several hydrolytic reactions, producing a mixture of
CC       iron(III)-(N-(2,3-dihydroxybenzoyl)-L-serine) complex and salmochelin
CC       SX.
DR   A0A0H2V660, IROD_ECOL6 ;
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