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ENZYME entry: EC 3.1.1.111

Accepted Name
Phosphatidylserine sn-1 acylhydrolase.
Alternative Name(s)
Phosphatidylserine-specific phospholipase A(1).
Reaction catalysed
  • A phosphatidylserine + H(2)O <=> a 2-acyl-1-lyso-phosphatidylserine + a fatty acid
  • A 1-acyl-2-lyso-phosphatidylserine + H(2)O <=> glycerophosphoserine + a fatty acid
Comment(s)
The enzyme, which has described from mammals, is specific for phosphatidylserine and 2-lysophosphatidylserine, and does not act on phosphatidylcholine, phosphatidylethanolamine, phosphatidic acid or phosphatidylinositol.
Cross-references
BRENDA3.1.1.111
EC2PDB3.1.1.111
ExplorEnz3.1.1.111
PRIAM enzyme-specific profiles3.1.1.111
KEGG Ligand Database for Enzyme Nomenclature3.1.1.111
IUBMB Enzyme Nomenclature3.1.1.111
IntEnz3.1.1.111
MEDLINEFind literature relating to 3.1.1.111
MetaCyc3.1.1.111
Rhea expert-curated reactions3.1.1.111
UniProtKB/Swiss-Prot
Q5E9H0, PLA1A_BOVIN;  Q53H76, PLA1A_HUMAN;  Q8VI78, PLA1A_MOUSE;  
Q5RBQ5, PLA1A_PONAB;  P97535, PLA1A_RAT;  G5EEM9, PLA1_CAEEL;  

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