ENZYME entry: EC 3.1.1.111

PURL: https://purl.expasy.org/enzyme/EC/3.1.1.111

Accepted Name

phosphatidylserine sn-1 acylhydrolase

Alternative Name(s)

phosphatidylserine-specific phospholipase A1

Reaction catalysed

a 1,2-diacyl-sn-glycero-3-phospho-L-serine + H2O = a 2-acyl-sn-glycero-3-phospho-L-serine + a fatty acid + H(+)
a 1-acyl-sn-glycero-3-phospho-L-serine + H2O = sn-glycero-3-phospho-L-serine + a fatty acid + H(+)

Comment(s)

The enzyme, which has described from mammals, is specific for phosphatidylserine and 2-lysophosphatidylserine, and does not act on phosphatidylcholine, phosphatidylethanolamine, phosphatidic acid or phosphatidylinositol.

Cross-references

Rhea expert-curated reactions

3.1.1.111

ExplorEnz

3.1.1.111

IUBMB Enzyme Nomenclature

3.1.1.111

UniProtKB/Swiss-Prot

Q9H3Z7, ABHGB_HUMAN	Q80YU0, ABHGB_MOUSE	Q5XIL6, ABHGB_RAT
O46606, DDHD1_BOVIN	Q8NEL9, DDHD1_HUMAN	Q80YA3, DDHD1_MOUSE
Q5E9H0, PLA1A_BOVIN	Q53H76, PLA1A_HUMAN	Q8VI78, PLA1A_MOUSE
Q5RBQ5, PLA1A_PONAB	P97535, PLA1A_RAT	G5EEM9, PLA1_CAEEL

BRENDA

3.1.1.111

MetaCyc

3.1.1.111

KEGG Ligand Database for Enzyme Nomenclature

3.1.1.111

EC2PDB

3.1.1.111

MEDLINE

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.1.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.1.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-