ID 3.1.1.116 DE sn-1-specific diacylglycerol lipase. CA a 1,2-diacyl-sn-glycerol + H2O = a 2-acylglycerol + a fatty acid + H(+). CC -!- The enzyme, present in animals, is specific for the sn-1 position. CC -!- When acting on 1-acyl-2-arachidonoyl-sn-glycerol, the enzyme forms CC 2-arachidonoylglycerol, the most abundant endocannabinoid in the CC mammalian brain. DR Q9Y4D2, DGLA_HUMAN ; Q6WQJ1, DGLA_MOUSE ; Q5YLM1, DGLA_RAT ; DR Q8NCG7, DGLB_HUMAN ; Q91WC9, DGLB_MOUSE ; P0C1S9, DGLB_RAT ; //