ID   3.1.1.118
DE   phospholipid sn-1 acylhydrolase.
AN   PA-PLA1.
AN   phosphatidic acid-preferring phospholipase A1.
AN   phospholipase DDHD1.
CA   (1) a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + H2O = a 2-acyl-
CA   sn-glycero-3-phospho-D-myo-inositol + a fatty acid + H(+).
CA   (2) a 1,2-diacyl-sn-glycero-3-phosphate + H2O = a 2-acyl-sn-glycerol
CA   3-phosphate + a fatty acid + H(+).
CC   -!- The human enzyme shows broad specificity, and has a preference for
CC       phosphatidate over other phospholipids.
CC   -!- Unlike EC 3.1.1.32 it is also active against phosphatidylinositol.
CC   -!- It is not active toward acyl groups linked at the sn-2 position.
DR   O46606, DDHD1_BOVIN;  Q8NEL9, DDHD1_HUMAN;  Q80YA3, DDHD1_MOUSE;
//