ENZYME entry: EC 3.1.1.34
Accepted Name |
Lipoprotein lipase.
|
Alternative Name(s) |
Clearing factor lipase. |
Diacylglycerol lipase. |
Diglyceride lipase. |
Reaction catalysed |
Triacylglycerol + H(2)O <=> diacylglycerol + a carboxylate |
Comment(s) |
- Hydrolyzes triacylglycerols and diacylglycerol in chylomicrons and
low-density lipoprotein particles (VLDL).
- Human protein purified from post-heparin plasma (LPL) shows no
activity against triglyceride in the absence of added lipoprotein.
- The principal reaction sequence of that enzyme is triglyceride ->
1,2-diglyceride -> 2-monoglyceride.
- The hepatic enzyme (LIPC) also hydrolyzes triglycerides and
phospholipids present in circulating plasma lipoproteins.
|
Cross-references |
PROSITE | PDOC00110 |
BRENDA | 3.1.1.34 |
EC2PDB | 3.1.1.34 |
ExplorEnz | 3.1.1.34 |
PRIAM enzyme-specific profiles | 3.1.1.34 |
KEGG Ligand Database for Enzyme Nomenclature | 3.1.1.34 |
IUBMB Enzyme Nomenclature | 3.1.1.34 |
IntEnz | 3.1.1.34 |
MEDLINE | Find literature relating to 3.1.1.34 |
MetaCyc | 3.1.1.34 |
UniProtKB/Swiss-Prot |
P11151, LIPL_BOVIN; | P11153, LIPL_CAVPO; | P11602, LIPL_CHICK; |
P55031, LIPL_FELCA; | P06858, LIPL_HUMAN; | P11152, LIPL_MOUSE; |
O46647, LIPL_NEOVI; | P49060, LIPL_PAPAN; | P49923, LIPL_PIG; |
Q06000, LIPL_RAT; | Q29524, LIPL_SHEEP; |
|
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