ID 3.1.1.51 DE phorbol-diester hydrolase. AN diacylphorbate 12-hydrolase. CA phorbol 12,13-dibutanoate + H2O = phorbol 13-butanoate + butanoate + CA H(+). CC -!- Hydrolyzes the 12-ester bond in a variety of 12,13-diacylphorbols CC (phorbol is a diterpenoid). CC -!- This reaction inactivates tumor promoter 12-O-tetradecanoylphorbol- CC 13-acetate from croton oil. //