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ENZYME

ENZYME entry: EC 3.1.1.53

PURL: https://purl.expasy.org/enzyme/EC/3.1.1.53
Accepted Name
sialate O-acetylesterase
Reaction catalysed
  • N-acetyl-9-O-acetylneuraminate + H2O = N-acetylneuraminate + acetate + H(+)
  • N-acetyl-4-O-acetylneuraminate + H2O = N-acetylneuraminate + acetate + H(+)
Comment(s)
  • Acts on free and glycosidically-bound N-acetyl- or N-glycoloylneuraminic acid.
  • Acts mainly on 4-O- and 9-O-acetyl groups.
  • Also acts on some other O-acetyl esters, both cyclic and acyclic compounds, which are not sialic acids.
Cross-references
BRENDA3.1.1.53
EC2PDB3.1.1.53
ExplorEnz3.1.1.53
KEGG Ligand Database for Enzyme Nomenclature3.1.1.53
IUBMB Enzyme Nomenclature3.1.1.53
MEDLINEFind literature relating to 3.1.1.53
MetaCyc3.1.1.53
Rhea expert-curated reactions3.1.1.53
UniProtKB/Swiss-Prot
P0C0V9, HEMA_BRV1P0C0W0, HEMA_BRV2P59711, HEMA_CVBEN
P33468, HEMA_CVBFQ66165, HEMA_CVBG9P59710, HEMA_CVBL9
Q9QAR6, HEMA_CVBLSQ8V437, HEMA_CVBLUP31613, HEMA_CVBLY
P15776, HEMA_CVBMQ9QAQ9, HEMA_CVBOKQ9DR81, HEMA_CVBON
P59709, HEMA_CVBQQ5MQD1, HEMA_CVHN1Q14EB1, HEMA_CVHN2
Q0ZME8, HEMA_CVHN5P30215, HEMA_CVHOCP31615, HEMA_CVMA5
O92367, HEMA_CVMDVQ83356, HEMA_CVMJHP31614, HEMA_CVMS
Q8BB26, HEMA_CVP67Q8JSP9, HEMA_CVPIAO91262, HEMA_CVPV
Q9IKD2, HEMA_CVRSDQ9Q9G3, HEMA_HUTVP68762, HEMA_INCAA
P03465, HEMA_INCCAP07973, HEMA_INCENP07971, HEMA_INCGL
P17003, HEMA_INCHYP07975, HEMA_INCJHP17004, HEMA_INCKY
P07970, HEMA_INCMIP17005, HEMA_INCNAQ67387, HEMA_INCNB
P07968, HEMA_INCP1P07967, HEMA_INCP2P07966, HEMA_INCP3
P07974, HEMA_INCTAP68761, HEMA_INCYAP87691, HEMA_INCYB
Q8V3U0, HEMA_ISAV8Q70KP1, HEMA_PTV10Q9HAT2, SIAE_HUMAN
P70665, SIAE_MOUSEQ5RFU0, SIAE_PONABP82450, SIAE_RAT

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.1.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.1.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-