ID 3.1.1.55 DE acetylsalicylate deacetylase. AN aspirin esterase. CA acetylsalicylate + H2O = acetate + H(+) + salicylate. CC -!- Not identical with EC 3.1.1.1, EC 3.1.1.2, EC 3.1.1.7 or EC 3.1.1.8. CC -!- The activity of the liver cytosol enzyme is highest with acetyl CC esters of aryl alcohols, and thioesters are also hydrolyzed. CC -!- The microsomal enzyme also hydrolyzes some other negatively charged CC esters. CC -!- Best substrates were esters of salicylate with long-chain alcohols. //